Phase 4 N=35 Lamotrigine Bioequivalence
Epilepsy
Primary: AUC — 101346; 101393 ng*hr/ml
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=76 Generic Travoprost Versus Brand Name Travoprost in Patients With Primary Open Angle Glaucoma or Ocular Hypertension
Glaucoma, Primary Open Angle · Ocular Hypertension
Primary: Intraocular Pressure — 18.20; 18.44 mm Hg
Phase 4 N=52 Kidney Biopsy Controlled Trial of Calcineurin Inhibitor Withdrawal
Kidney Transplantation
Primary: Number of Participants With Graft Survival at 12 Months — 18; 12 Participants
Phase 4 N=36 Drug Concentration Analysis of Micafungin in Overweight, Obese, and Extremely Obese Volunteers
Obesity · Nutrition Disorders · Overweight
Primary: Serum Clearance of Micafungin
Phase 4 N=149 RHYTHM (Formerly Escape II Myocardium)
Rheumatoid Arthritis
Primary: Number of Participants With Myocardial FDG Uptake — 21; 4; 25; 1 Participants
Phase 4 N=231 The Effect of Liposomal Bupivacaine on Post Operative Pain and Narcotic Use After Bariatric Surgery
Bariatric Surgery Candidate · Pain, Postoperative
Primary: Morphine Equivalents — 8.3; 7.5 MEU
Phase 4 N=30 Pharmacokinetics of Inhaled Monodisperse Fluticasone Propionate
Healthy · Asthma
Primary: AUC Fluticasone Propionate (FP) — 188.2; 756; 978; 380.5 pg.h/ml — p=<0.05
Phase 4 N=1,275 Study of Oral Treatments for Hepatitis C
Chronic Hepatitis C
Primary: Sustained Virologic Response (SVR12) mITT With Imputation-Phase 1 and 2 EBR/GZR, SOF/LDV — 40; 516; 14; 335 Participants
Phase 4 N=50 Lower Third Molar Removal With 2% and 4% Articaine
Impacted Third Molar Tooth · Adverse Reaction to Other Local Anesthetics
Primary: Onset of Anesthetic — 1.5; 1.5 minutes — p=0.192
Phase 4 N=23 EXPAREL Infiltration in Subjects Undergoing Femoral Nerve Block With Bupivacaine HCl for Total Knee Arthroplasty
Pain
Primary: Maximum Plasma Concentration (Cmax) — 499; 775 ng/mL
Phase 4 N=154 Remission Evaluation of a Metabolic Intervention in Type 2 Diabetes With Forxiga
Type 2 Diabetes Mellitus
Primary: Number of Participants Achieving Drug-free Diabetes Remission in the Experimental Group Compared to the Control Group — 19; 13 Participants
Phase 4 N=7 Neural Mechanisms of Disulfiram Effects
Alcohol Use Disorder
Primary: Alcohol Use — 0 days
Phase 4 N=245 A Study of Subjects With Psoriatic Arthritis to Investigate the Effectiveness of Adalimumab Introduction Compared With Methotrexate Dose Escalation (CONTROL)
Psoriatic Arthritis
Primary: Percentage of Participants Achieving Minimal Disease Activity (MDA) (Non-responder Imputation [NRI]) (Part 1) — 13.1; 41.5 percentage of participants — p=< 0.001
Phase 4 N=31 Effect of Symbicort ® on GR in Sputum in COPD
Chronic Obstructive Lung Disease
Primary: GR-GRE Binding (Relative to Baseline) — 1.1; 1.8; 2.3; 2.1 Fold activation — p=0.003
Phase 4 N=11 Downmodulating Monocyte Activation for HIV-1 Associated Neurocognitive Disorders (HAND)
HIV Dementia
Primary: Change From Week 0 in Percentage of Blood Monocytes Expressing Surface Marker CD16 at 12 Weeks, as a Result of Treatment. — 1.14; 1.51 Fold change — p=0.39