N/A N=38 A Development Study to Evaluate a Full-Face Mask for the Treatment of Obstructive Sleep Apnea
Obstructive Sleep Apnea
Primary: Trial Mask Comfort — 7; 13; 3; 12 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=39 The Evaluation of the Toffee Mask for the Treatment of Obstructive Sleep Apnea
Obstructive Sleep Apnea
Primary: Toffee Mask Acceptability — 27; 12 Participants
Phase 2 N=22 Vaccine Therapy in Treating Patients With Stage IV HLA-A2 and HER2 Positive Breast or Ovarian Cancer Receiving Trastuzumab
HER2/Neu Positive · HLA-A2 Positive Cells Present · Stage IV Breast Cancer
Primary: Immune Response Measured by IFN-gamma Secreting PBMC Precursor Frequency by ELIspot and HLA-A2 Major Histocompatibility Complex Tetramer Analysis — 14; 4; 1; 16…
Phase 2 N=22 Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery : Revised Protocol
Atrial Septal Defect · Ventricular Septal Defect · Atrioventricular Septal Defect
Primary: L-citrulline Plasma Levels — 200.9; 34.1; 2405.9; 29.5 µmol/L
N/A N=48 Skeletal Muscle Diacylglycerol and Sphingolipids - Impact of Localization and Species on Insulin Resistance in Humans
Diabetes Mellitus, Type 2 · Pre-diabetes · Obesity
Primary: Percent Change in Insulin Sensitivity Compared to Baseline Measurement. — 31.8; 17.4; -4.8 Percent change
N/A N=50 Transmembrane Electromyography (TM-EMG) for the Assessment of Neuromuscular Function in the Oropharynx
Obstructive Sleep Apnea · Amyotrophic Lateral Sclerosis · Muscular Dystrophies
Primary: Proof of Diagnostic Consistency — 95.7; 78.1; 90 % agreement
N/A N=147 Fermented Soybean Supplementation Among Active Pulmonary Tuberculosis Patients With Standard Therapy in Indonesia
Pulmonary Tuberculosis · Body Weight Changes · Motor Activity
Primary: Change in Bodyweight on a Digital Weight Scale From Baseline at 2 Months — 2.80; 1.44 Kilogram
Phase 3 N=11 A Strategy to Improve Success of Treatment Discontinuation in Buprenorphine Responders
Opioid-use Disorder
Primary: Percent of Patients Successfully Transitioned Off Buprenorphine — 2; 3 Participants
N/A N=423 Neuropathic Pain After Orchidectomy and Sex Reassignment Surgery
Neuropathic Pain · Phantom Pain · Sex Reassignment Surgery
Primary: Incidence of Phantom Pain — 6; 0 Participants — p=0.013
Phase 4 N=102 Efficacy of Exparel (TM) on Post-operative Pain After Laparoscopic Gastric Bypass Using Circular EEA Stapler
Post-operative Pain Management
Primary: Post-Operative Pain — 49.4; 56.6 units on a Visual Analog Scale (VAS)
Phase 2 N=48 Phase 2 Study of OTL38 for Intra-operative Imaging of Folate Receptor-alpha Positive Ovarian Cancer
Ovarian Cancer
Primary: Sensitivity of OTL38 in Detecting Folate Receptor-alpha Positive Ovarian Cancer During Surgery. — 97.97 percentage of lesions
Phase 3 N=131 Phase III Study of Edasalonexent in Boys With Duchenne Muscular Dystrophy
Muscular Dystrophy, Duchenne
Primary: Change From Baseline in North Star Ambulatory Assessment (NSAA) — -1.5; -1.8 score on a scale
N/A N=119 Efficacy of the Quell Wearable Device for Fibromyalgia
Fibromyalgia
Primary: Patients' Global Impression of Change — 3.58; 3.24 score on a scale
Phase 2 N=212 A Study to Evaluate the Efficacy and Safety of Sirukumab in Confirmed Severe or Critical Confirmed Coronavirus Disease (COVID)-19
Critical Confirmed Coronavirus Disease (COVID)-19
Primary: Time to Sustained Improvement of at Least 2 Categories on 6-point Ordinal Clinical Recovery Scale (CRS): Primary Analysis Set — 17.00; 23.00 Days
Phase 2 N=290 A Trial of Mepolizumab Adjunctive Therapy for the Prevention of Asthma Exacerbations in Urban Children
Asthma
Primary: Number of Asthma Exacerbations During the Treatment Period — 0.96; 1.30 Exacerbations during treatment — p=0.027