392 trials
Breast Cancer
Primary: Number of Participants With Adverse Events as a Measure of Safety and Tolerability After 89Zr-Trastuzumab Administration — 1; 1 participants
Gliosarcoma · Recurrent Glioblastoma
Primary: Number of Patients With Adverse Events — 8; 4; 1; 0 Participants
Alzheimer's Disease · Dementia
Primary: Medication Appropriateness Index — 11.2; 9.4 units on a scale
Methadone or Buprenorphine Detoxoxification
Primary: Change in Methadone/Buprenorphine Dose to 0 mg for Successful Completion of Taper — 3; 2 Participants
Cutaneous Melanoma, Stage III · Cutaneous Melanoma, Stage IV
Primary: Number of Participants With Serious Adverse Events (SAEs) and/or Dose Limiting Toxicities (DLTs) — 6; 1; 0 Participants
Calcium Pyrophosphate Deposition Disease
Primary: ATP Levels in Synovial Fluid — 4.4; 31.4 nanomoles/ml
Sickle Cell Disease
Primary: Number Participants With Most Common Reported Drug Related Adverse Events — 6; 3; 3 Participants
Bioequivalence
Primary: PK Parameters — 283; 341; 189 ng*h/mL
Vascular Stiffness · Insulin Sensitivity
Primary: Change in Flow Mediated Dilation (FMD) Between Baseline and After 2 Hour Insulin Clamp — 11.8; 11.8; 8.9; 8.95 % change
Alcohol Drinking · Binge Drinking · Drinking Behavior
Primary: Stop Signal Task (SST) — 255; 215 milliseconds
Uveitis
Primary: Change in Mean Number of Uveitis Relapses Per Patient Between the 12 Month Study Period Compared to Baseline — 0.35; 0.58 Relapses Per Patient
Heat Effect
Primary: PK Parameter — 3.38; 30.75 ng/mL
Bioavailability
Primary: Total Area Under the Curve (AUC) 0-12 Hours — 19.99; 19.22; 19.22; 16.57 ng*h/mL
Cervical Intraepithelial Neoplasia Grade 2/3 · Cervical Squamous Cell Carcinoma In Situ · Cervical Squamous Intraepithelial Neoplasia 2
Primary: Feasibility of Intravaginal Use 5-FU and Imiquimod on Alternating Weeks in Women With Biopsy Confirmed High Grade Cervical Squamous Intraepithelial Lesions. — 4; 1…
Lateral Epicondylitis
Primary: Change From Baseline in Visual Analog Scale (VAS) at 6 and 12 Weeks — 3.57; 3.02; 2.93; 1.60 score on a scale — p=0.52