12,372 trials
Acne Vulgaris
Primary: Absolute Change in Mean Lesion Counts at Week 12 — -18.5; -13.3; -26.3; -18.7 lesion counts
Acne Vulgaris
Primary: Absolute Change in Mean Lesion Counts at Week 12 — -18.5; -13.8; -26.9; -16.7 lesion counts
Chemotherapy-induced Neutropenia
Primary: Double-Blind Phase: Duration of Severe Neutropenia in Cycle 1 — 1.0; 1.1 days
Hyperkalemia
Primary: Percentage of Responders — 25; 7 Participants — p=<0.001
Psoriasis
Primary: Proportion of Subjects Achieving a PASI-75 at 12 Weeks at Each of the 3 Dose Levels of Voclosporin. — 4; 14; 26; 44 Participants
Influenza Virus
Primary: Efficacy Endpoint: First-Occurrence Reverse Transcription-Polymerase Chain Reaction (RT-PCR) Confirmed Influenza A and/or B of Any Influenza Strain in Subjects ≥6 to <72…
Multiple Myeloma
Primary: Progression Free Survival (PFS) — 8.38; 7.33 Months
Severe Acute Respiratory Syndrome Coronavirus 2 · COVID-19
Primary: Time to Hospital Discharge — 7.0; 8.0 days — p=0.509
Metastatic Pancreas Cancer · Locally Advanced Pancreatic Cancer · Pancreatic Adenocarcinoma
Primary: Overall Survival — 226; 209 days — p=0.6647
Lung Neoplasms · Lung Cancer
Primary: Clinically Significant Events (CSE) — .530 proportion of participants
Pain · Nausea · Vomiting
Primary: Percentage of Participants With OINV Over 48 Hours — 8; 31; 4 Participants — p=<0.001
Chronic Rhinosinusitis (Diagnosis)
Primary: Pain Visual Analogue Scale (VAS) — 3.3; 2.3 units on a scale — p=<0.05
Presbyopia
Primary: Percentage of Participants Gaining 3 Lines or More in Mesopic, High-Contrast, Binocular Distance-Corrected Near Visual Acuity (DCNVA) With No More Than 5-Letter Loss in…
Resistant Hypertension
Primary: Change From Baseline to Week 4 of Double-blind Treatment in Mean Trough Sitting Systolic Blood Pressure (SiSBP) Measured by Automated Office Blood Pressure Measurement…
Parkinson Disease · Early Parkinson's Disease
Primary: Change in Total Unified Parkinson's Disease Rating Scale (UPDRS) Score (Defined as Sum of Parts II and III, Scores (0-160). — -7.98; -4.69; -5.32; -8.35 score on a scale…