N/A N=501 COVID-19 Patient Positioning Pragmatic Trial
COVID-19
Primary: Number of Participants Categorized on the Modified WHO Ordinal Scale by the Highest Level of Support on Day 5 — 109; 99; 15; 15 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=93 Effect of Switching From Cigarette Smoking to IQOS on Exercise Capacity
Smoking · Exercise Capacity
Primary: Maximal Oxygen Uptake (VO2max, Absolute Values) — 1878; 2027; 2197; 1950 mL/min
Phase 2 N=61 A Study of Modified Stem Cells in Traumatic Brain Injury (TBI)
Traumatic Brain Injury
Primary: Change From Baseline in Fugl-Meyer Motor Scale (FMMS) Score at Week 24 Among All Patients — 6.0; 11.0; 8.1; 2.3 Change in score on a scale from baseline — p=0.0401
Phase 1 N=24 Exploratory Ph I Trial of the Active IMP in Healthy Volunteers in Relation to COVID-19
Covid19
Primary: Pharmacokinetic Concentrations - (Maximum Plasma Concentration [Cmax]) — 57.2; 41.7; 46.5; 22.3 ng/mL — p=0.803
N/A N=6 The Development of a COVID19 Oral Vaccine Consisting of Bacillus Subtilis Spores
COVID-19 Pneumonia
Primary: Serum Neutralizing Receptor Binding Domain IgG Antibody Concentration — 0.2; 9.3; 35.8 ug/ml
Phase 2 N=48 A Trial to Evaluate the Pharmacokinetics and Safety of AVYCAZ(R) in Combination With Aztreonam
Bacterial Infection
Primary: Number of Participants With at Least One Grade 2 (Moderate) or Higher Treatment-emergent Adverse Event — 1; 0; 0; 1 Participants
Phase 2 N=14 Phase 1 Open-label Study to Evaluate Efficacy and Tolerability of TLC399 in Patients With Macular Edema Due to RVO
Central Retinal Vein Occlusion With Macular Edema · Branch Retinal Vein Occlusion With Macular Edema
Primary: Part 1: Dose-limiting Toxicity (DLT) — 1; 0 Participants
N/A N=297 WIC-Based Intervention to Promote Healthy Eating Among Low-Income Mothers
Cancer Prevention · Diet Modification · Vegetable Intake
Primary: Vegetable Intake Carotenoid Scores at 3 Months — 227.11; 269.98 units on a scale — p=0.001
N/A N=22 iBAILA - Investigating Brains & Activity to Improve Latino Aging
Sedentary Behavior · Cognitive Impairment
Primary: Community Healthy Activities Model Program for Seniors (CHAMPS) Physical Activity Questionnaire for Older Adults — 402.0; 315.0; 492.0; 326.3 Minutes per week
Phase 2 N=289 A 4-week Study to Evaluate the Efficacy and Safety of HP-5000 in Subjects With Knee Osteoarthritis
Osteoarthritis of the Knee
Primary: Evaluate Efficacy & Safety of HP-5000 Topical Patches in Subjects With Osteoarthritis of the Knee: Change in Osteoarthritis Pain Score — -6.3; -5.6; -5.2 score on a…
N/A N=50 VivaSight Double Lumen Tube for Single Lung Ventilation
Double Lumen Endotracheal Tube · Single Lung Ventilation
Primary: Number of Participants Requiring Flexible Fiberoptic Bronchoscopy — 25; 7 Participants
Phase 2 N=128 A Randomized Phase 2 Trial of TAS-114 in Combination With S-1 Versus S-1
Advanced or Metastatic Non-small Cell Lung Cancer
Primary: Progression-free Survival (PFS) Based on Central Independent Review — 3.65; 4.17 months — p=0.2744
Phase 2 N=31 TLC399 (ProDex) in Subjects With Macular Edema Due to Retinal Vein Occlusion (RVO)
Retinal Vein Occlusion · Macula Edema
Primary: Proportion of Subjects With BCVA Gain of 15 or More Letters From Baseline in the Study Eye — 1; 1; 1 Participants
Phase 2 N=534 Dexpramipexole Dose-Ranging Biomarker Study in Subjects With Eosinophilic Asthma
Eosinophilic Asthma · Asthma
Primary: Change in Blood Absolute Eosinophil Count From Baseline to Week 12 — 0.8980; 0.4031; 0.3056; 0.2051 ratio to baseline — p=<.0001
Phase 2 N=45 Long-term Safety and Efficacy of Ralinepag in Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension
Primary: Change From Baseline in Pulmonary Vascular Resistance — -52.2 dynes.sec/cm5