Phase 4 N=10 Feasibility Study of Extended-release Naltrexone (Vivitrol) in Drug Court Settings
Opioid-Related Disorders
Primary: Number of Participants With New Arrests — 2; 2 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=102 A Study of a Drug to be Used in Addition With Another Drug to Treat Adults With Uncontrolled Partial-onset Seizures
Epilepsy With Partial On-set Seizures
Primary: The Number of Subjects Completing 24 Weeks Adjunctive Therapy During Maintenance Phase — 36; 37 participants
Phase 4 N=237 Extended-Release vs. Oral Naltrexone Alcohol Treatment in Primary Care
Alcohol Dependence
Primary: Percentage of Participants With Alcohol Abstinence or Moderate Drinking — 29; 23 percentage of participants
Phase 4 N=11 Effect of an H1 Receptor Antagonist on Exercise Performance in Hypoxia
Hypoxia, Altitude
Primary: Performance Time — 17.03; 18.08; 16.32 minutes — p=0.047
Phase 4 N=19 Examination of the Effectiveness of Suvorexant in Improving Daytime Sleep in Shift Workers
Sleep Disorder, Shift-Work
Primary: Change in Average Total Sleep Time — 1.83; -0.33 hours/sleep opportunity — p=<0.05
Phase 4 N=32 Effect of Injectable Platelet-Rich Fibrin (i-PRF) in Initial Treatment of Chronic Periodontitis
Periodontitis
Primary: Periodontal Pocket Depth-PPD — 3.735; 3.696 mm — p=0.429
Phase 4 N=149 Quetiapine SR and Divalproex Sodium ER in the Treatment of Anxiety in Bipolar Disorder With Panic Disorder and/or GAD
Bipolar Disorder · Panic Disorder · Generalized Anxiety Disorder
Primary: Change From Baseline in the CGI-21 Anxiety — 4.9; 2.9; 3.4 score on a scale — p=<.05
Phase 4 N=42 Evaluation of Efficacy of Full-mouth Disinfection in Generalized Aggressive Periodontitis Patients
Aggressive Periodontitis
Primary: Probing Depth — 4.55; 4.80; 4.90; 2.71 mm — p=<0.01
Phase 4 N=164 Nitrofurantoin Administration for the Prevention of Short-Term Catheter Associated Urinary Tract Infection After Pelvic Surgery
Catheter-Associated Urinary Tract Infection
Primary: UTI — 15; 14 Participants — p=0.84
Phase 4 N=1,054 Oral Versus Intravenous Antibiotics for Bone and Joint Infections (OVIVA B&J)
Bone Infection · Joint Infection
Primary: The Frequency of Definite Failure of Infection Treatment. — 67; 74 Participants
Phase 4 N=20 Effectiveness of Ipratropium Bromide in Preventing Exercise-induced Bronchoconstriction in Athletes
Bronchospasm, Exercise-Induced
Primary: Spirometry and Specific Airway Conductance Measured by Body Plethysmography Before and After Exercise Challenge After Randomized Administration of Either Inhaled…
Phase 4 N=26 Methylphenidate for Attention Problems After Pediatric TBI
Traumatic Brain Injury · TBI · ADHD
Primary: Parent Outcome-Vanderbilt ADHD Parent Rating Scales (VADPRS) — 1.10; 1.47; .84; 1.14 units on a scale
Phase 4 N=89 The Potential for Clinical Dependence and Withdrawal Symptoms Associated With Valbenazine
Tardive Dyskinesia (TD)
Primary: Participants With Withdrawal-Emergent Adverse Events — 9; 13 Participants
Phase 4 N=26 Beta Blockade in in Traumatic Brain Injury
Brain Injuries, Traumatic
Primary: Mortality — 7.7; 33.3 percentage of participants
Phase 4 N=225 Adult Oral Ibuprofen Study for ED Pain Patients
Pain, Acute
Primary: Pain Reduction at 60 Minutes From Baseline of the 3 Oral Ibuprofen Groups — -2.12; -1.85; -1.96 units on a scale