Clinical Trial Search

Primary: Change in Visual Analog Score From Baseline to Day 14 — -5.1 score on a scale

Primary: Number of Participants With Geometric Mean Antibody Concentrations by HPV Type — 15; 12; 8; 4 Participants

Primary: Number of Participants With Treatment-emergent Adverse Events (TEAEs) — 6; 3; 1; 50 Participants

Primary: Overall Surgeon Satisfaction of the Clinical Outcome of Eye Implanted With the TECNIS Toric II — 100; 0 Percentage of eyes

Primary: Lateral Kinematics Translations While Ascending Ramp — 0.1; -0.4 mm

Primary: Whole Body Fat Mass — 20.8 percentage of fat mass

Primary: International Restless Legs Syndrome (IRLS) Total Score Change From Baseline on Day 42 — 24.1; 24.5; 15.6; 18.7 score on a scale

Primary: Number of Participants Experiencing Graft Failure — 0; 0; 0 Participants

Primary: Change in Lipid Content of the Liver (Intrahepatocellular Lipid) — 27.9; 9.3; 21.4; 5.9 % IHCL — p=<0.05

Primary: Number of Patients With Adverse Events — 18 Participants

Primary: Change From Baseline in the Blood Phenylalanine (Phe) Concentration — 1022.4; -553.5; -653.3; -672.3 μmol/L

Primary: Change From Baseline in Total NPS at Week 40 — -0.36; 0.17 Score on a scale — p=<0.0001

Primary: Double Masked Period: Incidence of Ocular TEAEs — 3; 8; 1; 3 eyes

Primary: Lateral Condyle Kinematic Translations - Step up — 1.15; 2.28 mm

Primary: Medial Condylar Separation With Brace — 0.60 mm