Phase 4 N=43 Effect of Gender and HIV Infection on Zidovudine and Lamivudine Pharmacokinetics
HIV
Primary: ZDV-TP Drug Levels Compared Between HIV Negative and HIV Infected Subject — 33.89; 29.7 pmol/10^6 cells
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=822 Genetically Informed Smoking Cessation Trial
Smoking Cessation
Primary: 7-day Point Prevalence Quit Rate — 55; 70; 24 Participants
Phase 4 N=17 Ketamine Infusion for Adolescent Depression and Anxiety
Major Depressive Disorder · Anxiety Disorder
Primary: Montgomery-Asberg Depression Rating Scale Score 1 Day After Infusion — 15.44; 24.13 units on a scale
Phase 4 N=112 ACL Repair and Multimodal Analgesia
Pain
Primary: Opioid Consumption in the Immediate Postoperative Period — 12.0; 14.4 morphine mg equivalents
Phase 4 N=395 Treatment of Mild Gestational Diabetes With Glyburide Versus Placebo
Mild Gestational Diabetes
Primary: Mean Fetal Weight at Birth — 3355; 3322 grams
Phase 4 N=36 Investigation of the Role of Steroids in Enhancing Voice Therapy Outcomes
Dysphonia
Primary: Change in Consensus Auditory-Perceptual Evaluation of Voice (CAPE-V) Score From Baseline to 2 Months — 0.72; 0.65 score on a scale
Phase 4 N=82 Ketamine in the Treatment of Suicidal Depression
Major Depressive Disorder · Suicidal Ideation
Primary: Change in Scale for Suicidal Ideation — -3.66; -8.62 units on a scale
Phase 4 N=40 EBR/GZR for HCV-1b Patients Receiving Hemodialysis
Hepatitis C
Primary: Sustained Virologic Response (SVR12) Rate — 38 Participants
Phase 4 N=120 Diphenhydramine as an Adjunctive Sedative in Patients on Chronic Opioids
Colonoscopy · Adjunct Anesthesia Medication
Primary: Dosage of Fentanyl — 125.4; 126.9 (μg)
Phase 4 N=12 Durability and Impact of the Seasonal Influenza Vaccine on H5 Induced B Cell Response
Influenza A Subtype H5N1 Infection
Primary: Number of Participants With a Four-fold Increase in Stem-specific Antibody Titers (H5, Hemagglutinin Antibody) Against H5N1 at Day 29 After Vaccination With the Seasonal…
Phase 4 N=50 Post-Op Lidocaine Patch
Pain, Postoperative
Primary: 12-hour Postoperative Pain Scores — 33.5; 28.8 score on a scale
Phase 4 N=82 Study to Explore the Effect of Secukinumab, Compared to Placebo, on Fat Tissue and Skin in Plaque Psoriasis Patients
Plaque Psoriasis
Primary: Number and Percentage of Participants With Response of Psoriasis Skin Lesions to Treatment at Week 12 — 43; 1 Participants
Phase 4 N=25 Dropless™ vs. Less Drops™ Pharmaceutical Regimens After Cataract Surgery
Intraocular Lens Associated Postoperative Inflammation
Primary: The Change in Intraocular Pressure (IOP) From Baseline
Phase 4 N=6 Treatment of Sleep Disordered Breathing In Acute Decompensated Heart Failure Patients
Heart Failure · Sleep Apnea Syndromes
Primary: Reduction in Episodic Oxygen Desaturation
Phase 4 N=84 Impact of Local Anesthetic Wound Infiltration on Postoperative Pain Following Cesarean Delivery
Pain
Primary: Pain Score on Movement (Sitting in Bed From a Supine Position) — 5; 5 score on a scale