Phase 4 N=74 Fall Prevention in Older Adults With OAB
Overactive Bladder
Primary: Measure of Physical Activity — 1634.19 steps per day
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=222 An Open-label Study to Evaluate Correct Use and Ease of Use of the ELLIPTA DPI in Pediatric Subjects With Asthma
Asthma
Primary: Percentage of Participants From Each Stratum Who Demonstrated Correct Use of the ELLIPTA DPI at Visit 2, Attempt 1 (Day 28) — 92; 93 Percentage of participants
Phase 4 N=50 Apixaban for Primary Prevention of Venous Thromboembolism in Patients With Multiple Myeloma
Venous Thromboembolism · Multiple Myeloma
Primary: Frequency of Symptomatic Venous Thromboembolism — 0 Participants
Phase 4 N=795 Effects of Sacubitril/Valsartan Therapy on Biomarkers, Myocardial Remodeling and Outcomes.
Heart Failure
Primary: Change in Concentration of N-terminal Pro-brain Natriuretic Peptide (NT-proBNP) From Baseline to One Year — 0.5905 pg/mL — p=<.0001
Phase 4 N=10 Immune Response to Shingles Vaccination
Shingles
Primary: Percentage of Th1 Cytokine Positive VZV-specific CD4 T-cells in Blood — 0.02 percentage of CD4 T cells
Phase 4 N=56 Canadian Hemophilia Prophylaxis Study
Severe Hemophilia A
Primary: Number of Participants Who Developed Target Joint Bleeding — 17 Participants
Phase 4 N=694 Methotrexate Withdrawal Study of Tofacitinib Modified Release Formulation in Subjects With Rheumatoid Arthritis
Rheumatoid Arthritis
Primary: Double Blind Phase: Change From Randomization in Disease Activity Score in 28 Joints Using 4 Variables (DAS28-4) (Erythrocyte Sedimentation Rate [ESR]) at Week 48…
Phase 4 N=1,790 Melancholic Depression and Insomnia as Predictors of Response to Quetiapine in Patients With Major Depression
Depressive Disorder, Major
Primary: Number of Participants With 50 Percent Or Greater Reduction in the MADRS Score Over Time for the Quetiapine XR 150-300mg and Placebo 2 Arms/Groups Stratified by…
Phase 4 N=14 Perioperative Administration of Tranexamic Acid for Placenta Previa and Accreta Study
Placenta Accreta · Postpartum Hemorrhage · Cesarean Section
Primary: Estimated Blood Loss (EBL) — 3116; 9420 cc
Phase 4 N=105 Bupropion for ADHD in Adolescents With Substance Use Disorder
Attention Deficit Hyperactivity Disorder · Nicotine Dependence · Cannabis Use Disorder
Primary: Change in ADHD Rating Scale (ADHD-RS) Total Score — -14.2; -13.8 units on a scale
Phase 4 N=189 Differentiating Unipolar and Bipolar Depression in Young Adults Using fMRI
Bipolar Disorder · Major Depression
Primary: HAM-D 17 Item: Hamilton Depression Rating Scale — 6.6; 4.91; 2.333; 3.75 score on a scale
Phase 4 N=130 High vs Low Dose Dexamethasone on Complications in the Immediate Postoperative Phase After Mastectomy
Dexamethasone · Glucocorticoids · Mastectomy
Primary: Transfer to Post-anesthesia Care Unit (PACU) — 23; 23 Participants — p=1
Phase 4 N=138 Incontinence & Intimate Partners: Assessing the Contribution of Treatment
Urge Urinary Incontinence
Primary: Baseline Sexual Satisfaction Between Matched Female and Male Partners — 4.2; 4.8 score on a scale — p=.16
Phase 4 N=45 Optimizing Local Anesthetic Concentration for Continuous Femoral Nerve Blocks
Total Knee Arthroplasty · Knee Pain
Primary: Quadriceps Femoris Muscle Strength Maximum Voluntary Isometric Contraction (MVIC) — 13; 12 newtons — p=0.05
Phase 4 N=54 Long Term Safety and Efficacy Study of Calcitriol 3 mcg/g Ointment in Pediatric Subjects With Plaque Psoriasis
Psoriasis Vulgaris
Primary: Change From Screening in Serum Albumin Levels at Week 4 — -1.0 gram per liter (g/L)