65,437 trials
Anti-Bacterial Agents · Respiratory Tract Infections
Primary: Percentage of Patient-visits Prescribed an Antimicrobial at Their ED Visit — 21.2; 20.9; 19.1; 21.6 percentage of visits prescribed an abx — p=0.35
Depression
Primary: Depression (PHQ-9 Instrument) — 6.48; 5.84; 3.44 score on a scale
Healthy Volunteers
Primary: Period 1: Percent Absolute Bioavailability (%F) for TAK-831 — 17.34 percent absolute bioavailability
Magnetic Resonance Imaging
Primary: Degree of Lesion Contrast Enhancement — 0.884; 0.863; 3.007; 2.979 Scores on a scale — p=< 0.0001
Type 2 Diabetes Mellitus
Primary: Change in HbA1c From Baseline at Week 24 — -0.51; -0.10 % of HbA1c — p=0.0012
Alzheimer's Disease
Primary: Number of Participants With Adverse Events — 18; 21; 21 Participants
Depression · Anxiety · Physical Disability
Primary: Number of Participants Attending More Than 50% of Intervention Sessions and Number of Participants Reporting Satisfaction With the Intervention Sessions — 118; 63; 58…
Exposure During Pregnancy
Primary: Number of Participants With Serious Adverse Events (SAEs) — 0; 1; 1; 1 Participants
Smoking Cessation · Alcohol Drinking
Primary: Number of Participants Who Self-report Prolonged Abstinence From Smoking — 3; 0 Participants
Healthy Volunteers
Primary: Maximum Observed Plasma Concentration (Cmax) of GDC-9545 — 126; 129; 102 nanograms per millilitre (ng/mL)
Acromegaly
Primary: Percentage of Participants Diagnosed With Acromegaly — 5.8; 2.4 percentage of participants
Chronic Hemodialysis (ESRD)
Primary: Rate of Hypotension, Serious Adverse Events, GI Events and Cardiovascular Death — 1; 6; 5; 3 Participants — p=0.04
Hypermetabolic Lymphadenopathy Mediastinum Lower, Posterior and Middle, Detected by PET-CT With 18F-FDG (PET)
Primary: Sensitivity of Endoscopic Ultrasound-guided (EUS-guided) Puncture — 93 percentage
Healthy Volunteer Safety Study
Primary: Number Adverse Events (AEs) — 7; 2; 1; 9 adverse events
Type 2 Diabetes Mellitus
Primary: Change From Baseline in HbA1c at 24 Weeks — -0.59; -0.31 percentage of glycated hemoglobin — p=0.0026