65,437 trials
Healthy Volunteers
Primary: Percentage of Participants With Cellular Immune Response to 2 Doses of Tetravalent Dengue Vaccine (TDV) at 1 Month Post Second Vaccination — 97.1 percentage of…
Hiv
Primary: Quality of Life/Well-being (Young People) — 4.77 score on a scale
Opioid Withdrawal
Primary: Overall Occurrence of Treatment Emergent Adverse Events (TEAEs) — 270 Participants
Disorder of Urinary Stent · Ureteral Spasm · Ureteropelvic Junction Obstruction
Primary: Incidence of Post-operative Severe Pain (Pain Score ≥ 7) — 2; 1 Participants
Heart Failure With Reduced Ejection Fraction
Primary: Percentage of Patients Achieving the Target Dose of LCZ696 200 mg Bid at 10 Weeks Post Randomization — 224; 248 Participants — p=0.099
HER2-Positive Early Breast Cancer
Primary: Percentage of Participants by Their Preferred Method of Pertuzumab and Trastuzumab Administration, as Assessed in Question 1 of the Patient Preference Questionnaire…
Ischemic Stroke
Primary: Upper Extremity Fugl-Meyer Score — 18; 14 Participants — p=0.62
Healthy · Thiamine and Niacin Deficiency States · Pyridoxine Deficiency
Primary: Serum Thiamine — 50.21; 48.33; 51.21; 50.60 "µg/L"
COVID-19
Primary: Time to Recovery — 7.0; 8.0 Days — p=0.047
Ischemic Cardiomyopathy
Primary: Change From Baseline in Left Ventricular Ejection Fraction (LVEF) — -0.42; 0.37; 1.05; -0.33 percentage of end diastolic volume — p=0.993
Advanced Solid Tumors · Metastatic Solid Tumors
Primary: Maximum Tolerated Dose (MTD) — 10.0 mg/kg KW-0761IV
Preoperative Skin Preparation
Primary: Antimicrobial Activity of the Investigational Products Compared to Control. — 3.85; 3.91; 3.87; 3.84 log10 CFU/cm^2
Asthma
Primary: Asthma Control as Determined by Test for Respiratory and Asthma Control in Kids Assessment Tool — 70; 75; 85; 80 score on a scale
Evaporative Dry Eye
Primary: Tear Evaporation Rate With Nesofilcon A — 0.81; 0.88; 0.92 % relative humidity per second
Neuropathic Pain · Diabetic Peripheral Neuropathy (DPN) · Post Herpetic Neuralgia (PHN)
Primary: Absolute Change in Mean Pain Score, Using an 11 Point Numeric Pain Rating Scale (NPRS) — -0.87; -0.74 score on a scale — p=0.67