65,437 trials
Small Cell Lung Cancer · Gastric Adenocarcinoma · Esophageal Adenocarcinoma
Primary: Clinical Benefit Rate (CBR) at 24 Weeks of PDR001+LAG525 by Tumor Type in Multiple Solid Tumors and Lymphoma — 25; 3; 2; 5 Participants
Chronic Hand Eczema
Primary: Investigator's Global Assessment for Chronic Hand Eczema (IGA-CHE) Score of 0 (Clear) or 1 (Almost Clear) With at Least a 2-step Improvement (IGA-CHE Treatment Success)…
Metastatic Breast Cancer
Primary: Treatment-Emergent Adverse Events (TEAEs) — 106; 99; 506 adverse events
Stress Disorders, Post-Traumatic
Primary: Change in PTSD Checklist (PCL) — -5.6; -6.8; -4.8; -6.8 score on a scale
Endogenous Cushing's Syndrome
Primary: Normalization in Urinary Free Cortisol in Patients With Endogenous Cushing's Syndrome. — .30 proportion of subjects meeting endpoint — p=0.0154
Skin Cancer
Primary: MMSS for Scar Halves Treated — 8.4; 8.7 score on a scale
Healthy
Primary: Fecal Excretion of Radioactivity Over Time Expressed as a Percentage of the Total Radioactive Dose Administered — 31.3 percentage of the total radioactive dose
Rheumatoid Arthritis
Primary: Change From Baseline in Disease Activity Score in 28 Joints - C-reactive Protein (DAS28-CRP) at Week 12 — -0.75; -1.10; -2.10; -2.43 score on a scale — p=0.38
Diffuse Large B Cell Lymphoma · Primary Mediastinal Lymphoma · Mantle Cell Lymphoma
Primary: Part A: Effect of CYP3A Inhibition by Fluconazole on the PK of Tazemetostat (AUC0-t, AUC0-8) — 1340; 4100 h*ng/mL
Primary Care
Primary: Self-reported Bodily Pain — 2937; 1061; 1446; 2344 Participants
Chronic Pain
Primary: Oxytocin Concentration — 1047 pg/ml
Acute Kidney Injury · Exercise
Primary: Change in Concentration of Proenkephalin-A From Baseline to 4 Time-points Surrounding the Workout — 1.65; 3.69; 2.50; 2.13 pmol/L
Seasonal Influenza · Influenza · Influenza Due to Unspecified Influenza Virus
Primary: Cell Mediated Immune (CMI) Responses After In-vitro Restimulation Of Peripheral Blood Mononuclear Cells (PBMC) Following Vaccination. — 631; 655; 1560; 1137 Cells per…
Bifascicular Block · Syncope
Primary: Combined Endpoint Defined as First Occurrence Among the Following Events 1)Syncope Episode of Any Origin; 2)Presyncopal Episode With Documented Cardioinhibitory Origin…
Localized Hepatocellular Carcinoma
Primary: Number of Participants With Objective Tumor Response at 6 Months by MRI (Magnetic Resonance Imaging) — 75; 73 participants