65,437 trials
Trigeminal Nerve Injuries · Post-herpetic Neuralgia · Facial Pain
Primary: Visual Analogue Scale (VAS) — 5.4 score on a scale
Hypogonadotropic Hypogonadism
Primary: Change From Baseline in Log-Transformed Testicular Volume (TV) to Week 64 — 1.5; 14.5 mL
Macular Degeneration
Primary: Mean Change in Early Treatment Diabetic Retinopathy Study (ETDRS) Best-corrected Visual Acuity (BCVA) Letter Score for the Study Eye — -0.3; -0.5 Letters read correctly…
Follicular Lymphoma
Primary: Primary Efficacy Endpoint - Overall Response Rate by 7 Months — 108; 104 Participants
Advanced Hepatocellular Carcinoma · Liver Cancer · Hepatic Cancer
Primary: Time to Progression (TTP) Following CS1008 in Combination With Sorafenib Compared to Sorafenib Alone in Participants With Advanced Liver Cancer — 2.8; 3.0; 3.9 months
Substance Use Disorders · Contingency Management · Addiction, Cocaine
Primary: Pattern of Crack Cocaine Use — 14.3; 40.7 percent of negative cocaine samples
Dental Caries
Primary: Caries Activity and Progression Assessment Using LASER Fluorescence Readings by Diagnodent® Device. — 18.6; 1.1 units on a scale
Chronic Iron Overload
Primary: Percentage of Successfully Chelated Patients — 69; 80 Participants
Glycogen Storage Disease Type II;Pompe's Disease
Primary: PAP: Change From Baseline in Percent Predicted FVC in Upright Position at Week 49 — 2.89; 0.46 percent predicted FVC — p=0.0074
Stress Disorders, Post-Traumatic
Primary: Change From Baseline in UCLA Posttraumatic Stress Disorder (PTSD) Reaction Index for DSM 5 (Child Self-report) — -13.3; -17.8; -9.8 score on a scale
Symptomatic Venous Outflow Obstruction in the Iliofemoral Vein
Primary: Number of Participants With 30-day Freedom From Major Adverse Events — 232 Participants — p=<0.0001
Hearing Loss, Sensorineural · Hearing Loss, Conductive · Hearing Loss, Mixed Conductive-Sensorineural
Primary: Experimental Middle Ear Test: Ambient Wideband Absorbance — 0.39; 0.38; 0.32 Ratio
Chronic Obstructive Pulmonary Disease (COPD)
Primary: Change From Baseline in Residual Volume (RV) at 6 Hours Postdose — 0.004; -0.319 L — p=0.0987
Aortic Stenosis
Primary: Death — 12 Participants
Coronary Artery Disease
Primary: Final Fractional Flow Reserve (FFR) After Intracoronary Stenting — 0.80; 0.84; 0.88 Ratio