Phase 2 N=30 Afrezza Safety and Pharmacokinetics Study in Pediatric Patients
Type 1 Diabetes Mellitus
Primary: Insulin Maximum Observed Concentration (Cmax) — 28.5; 102; 101; 133 μU/mL
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=55 Phase II MEDI4736 in Combination With Chemotherapy for First-Line Treatment of Unresectable Mesothelioma
Mesothelioma · Pleural Mesothelioma
Primary: Overall Survival (OS) — 20.4 months
Phase 2 N=26 Phase 2 Sequential and Concurrent Chemoradiation for Advanced Nasopharyngeal Carcinoma (NPC)
Stage II Lymphoepithelioma of the Nasopharynx · Stage II Squamous Cell Carcinoma of the Nasopharynx · Stage III Lymphoepithelioma of the Nasopharynx
Primary: Number of Participants With Progression-free Survival (PFS) at 2 Years After Chemo-radiotherapy — 18; 4 Participants
Phase 3 N=150 Evaluation of the Immunogenicity and Safety of VARIVAX™ in Healthy Russians (V210-058)
Varicella
Primary: Varicella Zoster Virus (VZV) Antibody Response Rate at 6 Weeks Post Last Vaccination in Participants Who Were Seronegative at Baseline — 100.0; 100.0; 95.5; 100.0…
N/A N=20 Clinical Trial of a Rehabilitation Game - SuperBetter
Concussion · Mild Traumatic Brain Injury · Moderate Traumatic Brain Injury
Primary: Participation — 14 Participants
Phase 2 N=515 Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial Cancer
Gastric Adenocarcinoma · Esophageal Cancer · Hepatocellular Carcinoma
Primary: Percentage of Participants Experiencing Any Treatment Emergent Adverse Events and Serious Treatment Emergent Adverse Events — 100.0; 100.0; 100.0; 99.8 Percentage of…
Phase 4 N=315 PV-Isolation With the Cryoballoon Versus RF:a Randomized Controlled Prospective Non-inferiority Trial (FreezeAF)
Atrial Fibrillation
Primary: Combined Endpoint Out of: Absence of Atrial Arrhythmias and Absence of Persistent Complications at Six Months After the Index Procedure — 99; 98 Participants
N/A N=292 The Effects of Ambient Temperature and Forced-air Warming on Intraoperative Core Temperature
Major Surgery Under General Anesthesia
Primary: Rate of Core Temperature Change — -0.18; 0.05; -0.06; 0.07 degree C — p=<0.05
N/A N=53 OCT Pilot in Esophagus
Barrett Esophagus
Primary: Percentage of Imaged Sites Correctly Categorized as Squamous Mucosa — 93.1 percentage of imaged sites
Phase 1 N=76 Dose-Escalation Study Of Palbociclib + Nab-Paclitaxel In mPDAC
Metastatic Pancreatic Ductal Adenocarcinoma
Primary: Number of Participants With Dose Limiting Toxicities — 0; 1; 0; 0 Participants
Phase 3 N=191 A Dose-finding and Confirmatory Trial of OPC-6535 in Patients With Active Crohn's Disease
Crohn's Disease
Primary: Clinical Improvement Rate (Number of Subjects Showing Clinical Improvement / Number of Subjects Evaluated × 100) After 8 Weeks of IMP Administration — 31.3; 21.0; 29.5…
N/A N=42 Family Based Mindfulness Intervention
Parental Stress · Parent and Child Stress · Parental and Child Obesity
Primary: Attendance — 5.7; 7.1 Sessions — p=<0.015
Phase 4 N=75 Relationship Between Insulin Resistance and Statin Induced Type 2 Diabetes, and Integrative Personal Omics Profiling
Hyperlipidemia · Insulin Resistance · Type 2 Diabetes
Primary: Steady-state Plasma Glucose (SSPG) — 130; 139 mg/dL — p=0.01
N/A N=23 Bridge Occlusion Balloon in Lead Extraction Procedure
C.Surgical Procedure; Cardiac · Cardiac Dysrhythmia · Disorder of Pacing Function
Primary: Number of Participants With Successful Balloon Occlusion of Superior Vena Cava — 18; 5 Participants
N/A N=2,240 Are Text Message Reminders an Effective Intervention for Improving the Uptake of Breast Screening?
Breast Screening
Primary: Attendance at Breast Screening — 661; 722 Participants — p=<0.001