12,372 trials
Dry Eye
Primary: Change From Baseline to 4 Weeks (Day 28) in Symptom Assessment in Dry Eye (SANDE) Questionnaire Score — 73.0; 72.7; 56.6; 57.2 Score on a scale — p=0.739
Prostate Adenocarcinoma · Stage I Prostate Adenocarcinoma AJCC v7 · Stage II Prostate Adenocarcinoma AJCC v7
Primary: Change in Urinary Domain of the Expanded Prostate Cancer Index (EPIC) at Two Years — -4.12; -5.06 units on a scale — p=0.98
Heart Failure
Primary: Percentage of Pairwise Comparisons With Wins of Clinical Benefit, a Composite of Death, Number of Heart Failure Events (HFEs), Time to the First HFE and ≥5-point…
Heart Failure
Primary: Time to First Event of Adjudicated Cardiovascular (CV) Death or Adjudicated Hospitalisation for Heart Failure (HHF) — 8.67; 6.86 Patients with event/100 pt-yrs at risk…
Bipolar Depression
Primary: Change From Baseline in Montgomery-Åsberg Depression Rating Scale (MADRS) Total Score — -16.70; -12.12 score on a scale — p=<0.0001
Pulmonary Arterial Hypertension
Primary: Number of Adverse Events — 450; 362; 126; 206 events
Trichotillomania · Skin-Picking
Primary: NIMH Trichotillomania Symptom Severity Scale (NIMH-TSS) — 12.38; 10.63 score on a scale
COVID-19
Primary: Number of Participants Who Progress by at Least One Level Higher on the Modified WHO Ordinal Scale — 0; 0; 0; 0 Participants
Non-small Cell Lung Cancer
Primary: Progression-free Survival (PFS) as Assessed by Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) — 6.6; 4.2 Months — p=0.00624
Severe Asthma
Primary: Number of Subjects With Adverse Events — 39 Participants
Cerebral Palsy
Primary: Oxygen Consumption (ml/kg/Min) — 14.82; 16.75; 28.77 ml/kg/min
Primary Biliary Cholangitis
Primary: Percentage of Participants With Response to Composite Endpoint of ALP <1.67 × Upper Limit of Normal [ULN], ≥15% Reduction in ALP, and Total Bilirubin ≤ ULN) at Month 3…
Hypertension
Primary: Difference in Resting CTTI Between Carvedilol CR (Beta-blocker) and Valsartan (ARB) in Combination With Lisinopril. — 2447; 2500 CTTI units (mmHg*beats/min) — p=<0.05
Friedreich's Ataxia
Primary: Change From Baseline to 11 Months in Maximum Consumption of Oxygen (mlO2/kg/Min) Using Cardiopulmonary Exercise Testing (CPET) — 0.05; 0.08 ml O2/min/kg — p=0.5858
Generalized Myasthenia Gravis
Primary: Change From Baseline In Myasthenia Gravis-Activities Of Daily Living (MG-ADL) Total Score At Week 26 — -3.1; -1.4 units on a scale — p==0.0009