Phase 4 N=109 Dexmedetomidine in Pediatric Tonsillectomy
Pediatric Adenotonsillectomy · Post Operative Analgesia
Primary: Amount of Post-Operative Rescue Morphine Required for Analgesia — 45.2; 37.0; 43.3; 36.5 ug/kg
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=105 Study of ISIS 703802 in Participants With Hypertriglyceridemia, Type 2 Diabetes Mellitus, and Nonalcoholic Fatty Liver Disease
NAFLD · Diabetes Mellitus, Type 2 · Hypertriglyceridemia
Primary: Percent Change From Baseline in Fasting Triglycerides Level at the Primary Analysis Time Point — -16; -36; -53; -47 percent change — p=0.0343
N/A N=350 Peripheral Intravenous Catheter Securement With Tissue Adhesive
Vascular Access Devices
Primary: IV Catheter Survival — 66; 55 Participants
Phase 2 N=15 CD19 /22 CAR T Cells (AUTO3) for the Treatment of B Cell Acute Lymphoblastic Leukemia (ALL)
B Acute Lymphoblastic Leukemia · Recurrent Childhood Acute Lymphoblastic Leukemia · Refractory Childhood Acute Lymphoblastic Leukemia
Primary: Number of Patients With Grade 3-5 Toxicities Occurring Within the Dose Limiting Toxicity (DLT) Period of AUTO3 Infusion — 4; 4; 6 Participants
N/A N=11 Single-arm Phase II Study of NDURE for Patients With HNC
Cancer of Head and Neck
Primary: Percent of Patients With a Delay Starting Post-Operative Radiation Treatment — 4 Participants
Phase 3 N=705 IXAZOMIB Plus Lenalidomide and Dexamethasone Versus Placebo Plus Lenalidomide and Dexamethasone in Adult Patients With Newly Diagnosed Multiple Myeloma
Multiple Myeloma
Primary: Progression Free Survival (PFS) — 21.8; 35.3 months — p=0.073
Phase 2 N=18 A Study to Evaluate the Clinical Pharmacology and Safety of C1-esterase Inhibitor Administered by the Subcutaneous Route
Hereditary Angioedema Types I and II
Primary: Modeled C1-esterase Inhibitor Functional Activity Trough Level — 30.3; 45.9; 80.6 percent functional activity
N/A N=13 Glutamine and Insulin Sensitivity in Type I Diabetes
Type I Diabetes Mellitus
Primary: Insulin Sensitivity — 0.1; 0.07 mL/kg/min per uU/mL
Phase 3 N=119 EQW, DAPA, EQW/DAPA, DAPA/MET ER and PHEN/TPM ER in Obese Women With PolycysticOvary Syndrome (PCOS)
Polycystic Ovary Syndrome · Obesity
Primary: Oral Disposition (Insulin Sensitivity-insulin Secretion) Index — 471; 311; 503; 395 index score — p=<0.02
N/A N=850 Analysing the Psychosocial Effects of COVID-19 Pandemic on Dental Professionals Using the Turkish Version of the Fear of COVID-19 and Coronavirus Anxiety Scales
COVID-19 Pandemic
Primary: The Psychosocial Effects of COVID-19 Pandemic on Dental Professionals Using the Turkish Version of the Fear of COVID-19 Scale — 18.48 scores on a scale
N/A N=40 INVSENSOR00027 Clinical Performance Study
Healthy
Primary: Sensitivity of INVSENSOR00027's Posture Change Detection — 100 percent sensitivity for posture change
Phase 1 N=14 Nintedanib and Weekly Docetaxel in Lung Adenocarcinoma
Carcinoma, Non-Small-Cell Lung
Primary: Maximum Tolerated Dose (MTD) of Nintedanib Administered in Combination With Docetaxel — NA milligram
Phase 2 N=70 L-Glutamine Therapy for Sickle Cell Anemia and Sickle ß0 Thalassemia
Sickle Cell Anemia · Thalassemia
Primary: Number of Occurrences of Painful Sickle Cell Crises — 4.5; 10.8 Crisis — p=0.076
N/A N=500 A Study of Two Types of Absorbable Surgical Sutures in the Suturing of Thyroid Surgery Incision
Sutures
Primary: Wound Healing Grade — 99.35; 98.73; 99.36 percentage
Phase 2 N=24 SV-BR-1-GM in Metastatic or Locally Recurrent Breast Cancer
Breastcancer · Breast Neoplasm
Primary: Number of Patients With Treatment Emergent Adverse Events Occurring in Two or More Patients [Safety] — 24; 11; 8; 7 Participants