Phase 4 N=63 Preoperative Gabapentin Versus Bisoprolol for Hemodynamic Optimization During Sinus Surgery
Blood Pressure
Primary: Changes in Surgical Field Visibility — 2; 2; 4; 1 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=776 A Study of the Efficacy and Safety of NVA237 in Patients With Moderate to Severe COPD
Chronic Obstructive Pulmonary Disease
Primary: Change From Baseline in Trough Forced Expiratory Volume in 1 Second (FEV1) at Week 12 — 0.092; 0.059 Liters — p=0.051
Phase 4 N=44 The Impact of Arousal Threshold in Obstructive Sleep Apnea
Obstructive Sleep Apnea
Primary: Apnea Hypopnea Index (AHI) — 50.0; 51.8 events/hour — p=0.576
Phase 4 N=114 Gabapentin as an Adjunct to Paracervical Block for Perioperative Pain Management
Pain
Primary: Pain at Time of Uterine Evacuation — 63.79; 62.21; 64.58; 66.12 score on a scale
Phase 4 N=74 An Assessment of Chronic Synovial-Based Inflammation and Its Role With Serum Urate Levels.
Gout
Primary: Number and Percentage of Participants With Evidence of Chronic Ongoing Synovial-Based Inflammatory Disease at Baseline. — 63 Participants — p=0.34
Phase 4 N=347 Effect of Nintedanib on Biomarkers of Extracellular Matrix Turnover in Patients With Idiopathic Pulmonary Fibrosis and Limited Forced Vital Capacity Impairment
Idiopathic Pulmonary Fibrosis
Primary: The Rate of Change (Slope) in Blood C-reactive Protein Degraded by Matrix Metalloproteinase-1/8 (CRPM) From Baseline to Week 12. — -0.00190; -0.00257 nanogram/ millitre/…
Phase 4 N=23 Bepreve vs. Alrex in Subjects With Moderate to Severe Allergic Conjunctivitis
Allergic Conjunctivitis
Primary: Change From Baseline in Ocular Itching at 14 Days — 2.17; 1.82 units on a scale
Phase 4 N=108 Combined Bleaching Technique: Efficacy and Tooth Sensitivity
Tooth Bleaching · Tooth Sensitivity
Primary: Tooth Sensitivity (TS) — 1; 1; 1; 0 score on a scale
Phase 4 N=1,053 Efficacy and Safety Study of Risedronate, Cholecalciferol Combination Tablet in Patients With Osteoporosis
Osteoporosis
Primary: The Change of Bone Mineral Density (BMD) Value — 0.77; 0.77; 0.81; 0.80 g/cm^2
Phase 4 N=82 To Compare the Effectiveness of Suvorexant vs Placebo on Sleep Pressure in Hypertensives With Insomnia
Hypertension · Insomnia
Primary: Change in Sleep Systolic Blood Pressure — -1.8; -4.4 mmHg
Phase 4 N=48 Effects of Losartan and Antiretroviral Regimen Containing Raltegravir in Fibrosis Inflammation Mediators, Cardiovascular Risk and Neurocognitive Disorders in HIV Infected Patients Previously Effectively Treated
HIV-1 Infection
Primary: Proportion of Patients With 50% Reduction of Fibrosis in Lymphatic Tissue. — 0; 0; 0; 0 participants — p=1
Phase 4 N=35 Phase IV Study of the Impact of Dietary Fibers on Symptoms and Esophageal Motility in Patients With Non-erosive GERD
Gastroesophageal Reflux Disease
Primary: Number of Gastroesophageal Refluxes — 42.4 refluxes — p=0.000002
Phase 4 N=196 Immunogenicity of Hepatitis B Vaccination in Methadone Maintenance Treatment Patients
Hepatitis B Vaccine
Primary: Number and Rate of Participants With Anti-HBs Seroconversion at Month 7 — 59; 62 Participants
Phase 4 N=32 GRASSP: Gralise® for Spine Surgery Pain
Post-laminectomy Pain Syndrome
Primary: Mean Change in Numeric Rating Scale (NRS) — -0.56; -0.54 units on a scale
Phase 4 N=28 Anti-Hepatitis A Virus, Pharmacokinetics, and Safety of Immune Globulin (Human)
Anti-Hepatitis A Antibody Levels in Heathy Subjects
Primary: Percentage of Subjects Maintaining Protective Anti- HAV Antibody Levels — 26 Participants