Phase 3 N=380 Safety and Efficacy of KPI-121 in Subjects With Postsurgical Inflammation
Ocular Infections, Irritations and Inflammations
Primary: Resolution of Anterior Chamber Cells — 48; 39; 19 Participants — p=.0024
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=151 A Safety, Efficacy and Pharmacokinetic Study of AGN-199201 and AGN-190584 in Patients With Presbyopia
Presbyopia
Primary: Weighted Average Change From Baseline in Uncorrected Near Visual Acuity (UNVA) Letters in the Nondominant Eye — 3.00; 4.96; 7.77; 7.54 letters correctly read — p=0.1663
Phase 3 N=41 Ketamine Infusion for Comorbid PTSD and Chronic Pain
PTSD · Chronic Pain
Primary: Impact of Event Scale-Revised (IES-R) — 36.33333333; 37; 10.44444444; 15.64705882 units on a scale
Phase 2 N=163 A Study of the Concurrent Use of AGN-190584 and AGN-199201 in Participants With Presbyopia
Presbyopia
Primary: Weighted Average Change From Baseline in Mesopic, High Contrast Uncorrected Near Visual Acuity (UNVA) Letters — 1.12; 3.83; 5.26; 5.42 letters correctly read — p=0.0029
Phase 2 N=225 Evaluation of Gallium-68-HBED-CC-PSMA Imaging in Prostate Cancer Patients
Prostate Cancer
Primary: Sensitivity of Ga-68 HBED-CC PSMA for Detection of Nodal Metastases — .59; .89 proportion of participants
Phase 3 N=1,462 Assessment of the Long-Term Safety and Efficacy of Bempedoic Acid (CLEAR Harmony OLE)
Hypercholesterolemia · Atherosclerotic Cardiovascular Disease
Primary: Number of Participants With Treatment-Emergent Adverse Events (TEAEs) — 385; 758; 1143; 97 Participants
N/A N=30 One Week Assessment of The Phenacite Lens
Myopia
Primary: Binocular Distance Visual Acuity (VA) - High Illumination High Contrast — -0.22; -0.24 logMAR
Phase 3 N=11,016 THALES - Acute STroke or Transient IscHaemic Attack Treated With TicAgreLor and ASA for PrEvention of Stroke and Death
Acute Ischaemic Stroke · Transient Ischaemic Attack
Primary: Composite of Subsequent Stroke or Death — 303; 362 Participants — p=0.015
Phase 4 N=88 Effects of Smoking Environments on Brain Reactivity
Cigarette Smoking
Primary: Signal Change in Functional Magnetic Resonance Imaging (fMRI) Contrast of Parameter Estimate (COPE) Between Personal Environment Pictures Relative to Non-Personal…
Phase 3 N=31 Supplementation of Glutamine and Fish Oil Versus Placebo in Patients With Heart Failure
Heart Failure
Primary: Baseline Skeletal Muscle Function Capacity- Isometric Contractions (PKTQ/BW) — 177; 196; 76; 90 Percent
Phase 3 N=95 Effect of Kuvan on Neurocognitive Function, Blood Phenylalanine Level, Safety, and Pharmacokinetics in Children With PKU
Phenylketonuria
Primary: Full-Scale Intelligence Quotient (FSIQ) Score — 101.06; 103.64; 104.69; 103.78 score on a scale
N/A N=380 The Role of Antimicrobial Foam Dressing in Prevention of Cesarean Section Wound Complications
Cesarean Section; Complications, Wound, Dehiscence
Primary: Number of Participants With Wound Disruption and/or Infection — 5; 9 Participants
N/A N=2,384 Modeling Clinical Failure in Prostate Cancer Patients Based on a Two-stage Statistical Model
Prostate Cancer
Primary: Number of Participants With Clinical Failure After Initiation of Radiotherapy — 315 Participants
N/A N=28 Peer-Delivered Whole Health Coaching for Veterans With PTSD
PTSD
Primary: Goal Attainment Scaling (GAS) — 2.33; 4.15; 4.63 score on a scale — p=<0.05
N/A N=35 NIRS Monitoring to Detect AKI in Preterm Infants
Acute Kidney Injury · Premature Infant
Primary: Renal NIRS Tissue Oxygenation Differential — 60; 32.4; 62.5; 44.4 percentage saturation — p=<0.001