Phase 2 N=184 SYL040012, Treatment for Open Angle Glaucoma
Open Angle Glaucoma · Ocular Hypertension
Primary: Change From Baseline in the Mean Diurnal IOP Within Each Treatment Arm — -2.4; -3.2; -3.1; -3.1 mmHg — p=0.93
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=10 Feasibility of HIIT in Spinal Cord Injury
Spinal Cord Injuries · Spinal Cord Diseases
Primary: HIIT Times — 10 Intervals
N/A N=117 Five-Plus Year Follow-Up of SMART Randomized Controlled Trial
Chronic Low Back Pain
Primary: LS Mean Reduction in Oswestry Disability Index (ODI) From Baseline — 25.95 units on a scale of 0 to 100 points — p=0.001
N/A N=8 ULCERS - Electrical Stimulation in Diabetic Foot Ulceration
Diabetes
Primary: Number of Day Until 50% Healing of Leg Ulcer — 55; 30 Days
N/A N=42 Improving Motor Function After Spinal Cord Injury
Spinal Cord Injury
Primary: Physiology Measurements Before and After rTMS/Sham rTMS Protocol- Changes in Amplitude of Motor Evoked Potential (MEP) From TMS — 0.31; 0.43; 0.45; 0.65 millivolts (mV)
Phase 2 N=259 A Study to Evaluate the Efficacy and Safety of Oral VT-1161 in Patients With Onychomycosis of the Toenail
Onychomycosis
Primary: The Proportion of Subjects in the Intent-to-treat Population With Complete Cure, Defined as Clinical AND Mycological Cure, at Week 48 — 17; 19; 22; 18 Participants
N/A N=97 Evaluation of Nucleus 6 Sound Coding Algorithms
Hearing Loss
Primary: Percentage of Words Correct on AzBio Sentences in Noise S0N90 — 72.1 percentage of words correct
Phase 3 N=418 Study of Efficacy and Safety of Xolair® (Omalizumab) in Chinese Patients With Chronic Spontaneous Urticaria
Chronic Spontaneous Urticaria
Primary: Change From Baseline of the Itch Severity Score (ISS7) Score After 12 Weeks of Treatment — -10.11; -9.66; -5.87 Score on a scale — p=<0.001
Phase 1 N=16 Effectiveness of Ivermectin as add-on Therapy in COVID-19 Management
COVID 19
Primary: Number of Cured Patients — 16 Participants
N/A N=164 Framingham State Food Study
Obesity · Diabetes · Cardiovascular Disease
Primary: Total Energy Expenditure, Assessed by Indirect Calorimetry Using Stable Isotopes — 2713; 2504; 2640; 190 kcal/d
Phase 3 N=150 Additive Homeopathy in Cancer Patients
Malignant Tumors
Primary: EORTC-QLQ-C30 Score — 51.2; 46.6 score on a scale — p=0.397
N/A N=119 Image-guided, Robotically Delivered Transcranial Magnetic Stimulation Treatment for Combat-Related Post-Traumatic Stress Disorder
Stress Disorders, Post-Traumatic
Primary: Change in PTSD Severity as Measured by the PTSD Checklist (PCL-5) — 59.82; 60.45; 33.29; 39.14 score on a scale
N/A N=160 SentiMag® Intraoperative Comparison in Breast Cancer
Breast Cancer
Primary: Number of Participants With Detected Lymph Nodes — 145 Participants
N/A N=36 Supporting Together Exercise and Play and Improving Nutrition
Obesity
Primary: Attendance — 11; 8; 2; 12 Participants
Phase 4 N=30 Safety and Tolerability of Repatha® (Evolocumab) in Indian Participants With Homozygous Familial Hypercholesterolemia
Homozygous Familial Hypercholesterolemia HoFH
Primary: Number of Participants With Treatment-Emergent Adverse Events (TEAEs) — 10 Participants