65,437 trials
Plaque Psoriasis
Primary: Percentage of Participants With Treatment Success of a 2-Grade IGA Score Improvement From Baseline and an IGA Score of Clear or Almost Clear at Week 8 — 52.5; 33.3…
Psoriasis
Primary: Percent of Subjects With Treatment Success, Defined by at Least a 2 Grade Improvement From Baseline in the Investigator Global Assessment (IGA) Score Equating to Clear…
Postoperative Pain Relief
Primary: A Mean Difference of Total Analgesic (Pethidine) Consumption. — 122.15; 55.5; 59.7 mg
Hematologic Malignancy · Myeloproliferative Disorder
Primary: Clinical Failure of Isavuconazole Prophylaxis by Week + 14 Post Hematopoietic Stem Cell Transplant (HCT) — 81; 3; 7; 4 Participants
Healthy Participants
Primary: Relative Bioavailability (Frel) of a Capsule Compared to a Liquid Formulation of IX-01 While Fasting, as Calculated by a Ratio of Area Under the Plasma Concentration…
Sickle Cell Anemia
Primary: Change in Qualitative Spleen Function From Randomized Control Trial Baseline Measurement - Compared Between Children Randomized to Hydroxyurea vs Placebo — 26; 28; 32…
Anemia, Sickle Cell
Primary: Change in Qualitative Spleen Function From Randomized Control Trial Baseline Measurement - Compared Between Children Randomized to Hydroxyurea vs Placebo — 16; 15; 44…
AIDS Dementia Complex · HIV-1-Associated Cognitive Motor Complex · Human Immunodeficiency Virus
Primary: Change From Baseline to Week 24 in Global Neuropsychological Performance — .24 units on a scale — p=0.0079
Atopic Dermatitis
Primary: Percentage of Participants With Eczema Area and Severity Index (EASI) 75 (≥75% Improvement From Baseline) at Week 16 — 29.6; 62.6; 59.1 Percentage of Participants — p=<…
Plaque Psoriasis
Primary: The Percentage of Participants With Treatment Success at Week 8 — 45.33; 12.51 percentage of participants
Recurrent Platinum Resistant Ovarian Cancer
Primary: Mean Objective Response Rate (ORR) by Independent Central Review (ICR) Using Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) — 15.3 percentage of…
Vaginal Vault Prolapse · Pelvic Organ Prolapse · Uterine Prolapse
Primary: Patient Global Impression of Improvement (PGI-I) Score — 39 Participants
Constipation
Primary: Percentage of Participants With a Spontaneous Bowel Movement (SBM) Within 1, 2, 3, 4, and 6 Hours of Treatment — 0; 0; 0; 7 Participants
Psoriasis Vulgaris
Primary: Time to First Relapse — 56; 30 days — p=<0.001
Psoriatic Arthritis
Primary: ACR20 (American College of Rheumatology 20% Improvement) Response Rate Through Week 16 — 41.8; 48.9; 24.7 Percentage of Participants