65,437 trials
Healthy Volunteers
Primary: Total Secreted Fluid Volume as Measured by MR-PFT — 79 mL
Islet Transplantation · Type1 Diabetes Mellitus
Primary: Percentage Time in Range 70-180 mg/dL by CGM — 77 percentage of CGM readings 70-180mg/dL
Insomnia
Primary: Change in Insomnia Severity Index - Total Score — -10.71; -8.84; -8.51; -9.30 units on a scale
Peripheral Artery Disease
Primary: Change From Baseline in Six-minute Walk Distance — 18.4; -24.2; 15.1; -2.9 meters
Rheumatoid Arthritis (RA)
Primary: Percentage of Participants With an American College of Rheumatology 20% (ACR20) Response at Week 12 — 31.4; 71.6 percentage of participants — p=<0.001
Age-Related Macular Degeneration
Primary: Phase I: Percentage of Participants With Adverse Events — 11; 10; 10 Participants — p=1.00
Glioblastoma · Glioblastoma Multiforme · Gliosarcoma
Primary: Phase 1- Determination of the Maximum Tolerated Dose (MTD) of Enzastaurin — 250 milligrams (mg)
Acute Pancreatitis · Intra-abdominal Hypertension
Primary: Percent Change of IAP After Treatment — -18.7; -5.4; -27.2; -20.0 percent change of IAP
Abortion in First Trimester
Primary: Worst Pain Measurement Via Numeric Rating Scale (NRS-11) — 8.0; 7.0; 7.5; 6.5 score on a scale — p=.20
Hypertension, Pulmonary
Primary: Maximum Observed Plasma Concentration (Cmax) After Administration of AMB Under Fasted Condition — 359.030; 316.505; 353.252 Nanogram per milliliter
Multiple Myeloma
Primary: Progression Free Survival (PFS) — 11.1 Months
Avian Influenza · Influenza · Influenza Immunisation
Primary: Geometric Mean Titers (GMTs) of Serum Hemagglutination Inhibition (HAI) Antibodies Against the 2017 H7N9 Inactivated Influenza Vaccine (IIV) Strain After Second H7N9…
Head and Neck Neoplasms · Head and Neck Cancer · Head and Neck Lymphedema
Primary: Fidelity/Adherence Via Subject Diary — 5; 1; 1; 2 Participants
Sarcopenia
Primary: Percentage of Whole Body Lean Mass (%WBLM) — 67.3; 61.9 % of whole body mass
Aortic Valve Stenosis
Primary: NYHA Improvement and AVA >= 0.65 cm2 — 14 Participants