Phase 2 N=200 Study of OPA-15406 Ointment in Patients With Atopic Dermatitis
Atopic Dermatitis
Primary: Responder Rate of Investigator's Global Assessment(IGA) of Disease Severity at Week4 — 14.93; 22.39; 9.09 percentage of participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 1 N=40 Phase 1 Study of TAK-831 in Healthy Adult Asian Subjects
Healthy Volunteers
Primary: Number of Participants Reporting at Least One Treatment-emergent Adverse Event (TEAE) — 0; 2; 0; 4 Participants
Phase 3 N=260 Study to Evaluate ISV-305 Compared to Vehicle for Treatment of Inflammation and Pain Associated With Cataract Surgery
Inflammation and Pain Associated With Cataract Surgery
Primary: Proportion of Participants With Anterior Chamber Cell (ACC) Grade 0 in Study Eye at Day 15 (Last Observation Carried Forward) in the Modified Intent to Treat (mITT)…
N/A N=1,512 Tracheal Intubation Coaching in NICUs
Failed or Difficult Intubation, Sequela · Intubation;Difficult · Intubation Complication
Primary: Number of Participants With Tracheal Intubation Associated Events (TIAEs) in the NICU Over 2 Years — 138; 214; 33; 51 Participants — p=0.015
Phase 3 N=1,200 A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 When Administered Concomitantly With Influenza Vaccine in Healthy Adults 50 Years of Age or Older (V114-021/PNEU-FLU)
Pneumococcal Infections
Primary: Percentage of Participants With a Solicited Injection-site Adverse Event — 10.7; 11.6; 68.5; 71.1 Percentage of Participants — p=0.617
Phase 2 N=101 Tadalafil and Lenalidomide Maintenance With or Without Activated Marrow Infiltrating Lymphocytes (MILs) in High Risk Myeloma
Multiple Myeloma
Primary: Feasibility of MILs as Assessed by the Ability to Harvest, Expand, and Infuse the MILs Product — 71; 46; 1; 4 Participants
Phase 2 N=20 Intraoperative Amiodarone to Prevent Atrial Fibrillation in Lung Transplant Patients
Atrial Fibrillation · Lung Transplant; Complications
Primary: Post Operative Atrial Fibrillation — 6 Participants
Phase 2 N=24 A TSEC for Symptom Management in Menopausal Women With Multiple Sclerosis
Menopause · Multiple Sclerosis
Primary: Hot Flash Related Daily Interference Scale (HFRDIS) Score — 4; 9 score on a scale
Phase 2 N=32 Ketoconazole and Dexamethasone in Prostate Cancer
Prostate Cancer
Primary: Number of Participants Who Achieved a Second Decline in Prostate Specific Antigen (PSA) Following Progression on First Regimen — 0 Participants
Phase 3 N=413 Efficacy and Safety of Elagolix in Combination With Estradiol/Norethindrone Acetate for the Management of Heavy Menstrual Bleeding Associated With Uterine Fibroids in Premenopausal Women
Uterine Fibroids · Heavy Menstrual Bleeding
Primary: Percentage of Participants Meeting the Criteria for Responder — 8.7; 84.1; 68.5 percentage of participants — p=< 0.001
Phase 3 N=603 BLI400-302: A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adults
Constipation · Chronic Idiopathic Constipation · CIC
Primary: Treatment Response — 77; 39 Participants — p=<0.001
N/A N=1,312 Vitamin D and Omega-3 Trial to Prevent and Treat Diabetic Kidney Disease
Diabetes
Primary: Change in Estimated Glomerular Filtration Rate — -12.3; -13.1; -12.2; -13.1 mL/min/1.73m2 — p=0.25
Phase 2 N=304 A Study of LY2623091 in Participants With High Blood Pressure
Primary Hypertension
Primary: Change From Baseline to 4 Weeks in Seated Systolic Blood Pressure (SBP) — -0.5; -13.1; -14.6; -14.3 millimeter of mercury (mmHg)
Phase 1 N=6 A Study of How the Body Breaks Down and Eliminates LY2623091
Healthy Volunteers
Primary: Urinary and Fecal Excretion of LY2623091 Radioactivity Over Time Expressed as a Percentage of the Total Radioactive Dose Administered — 60.5; 1.39 percentage of…
Phase 1 N=6 Pharmacokinetics (PKs) and Metabolism of Radiolabelled Linerixibat
Cholestasis
Primary: Period 1: Area Under the Concentration-time Curve (AUC) From Time Zero (Pre-dose) Extrapolated to Infinite Time (AUC[0-inf]) of Linerixibat and [14C]-Linerixibat…