Phase 3 N=19,474 The ARCT-154 Self-Amplifying RNA Vaccine Efficacy Study (ARCT-154-01)
COVID-19 Vaccines
Primary: Number of Participants Reporting Solicited Local Adverse Reactions (ARs) — 4060; 909; 467; 416 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=400 Effectiveness of an Evidence-based Stepped Care System for Alcohol and Other Drug Use Problems Among Congolese Refugees in Zambia
Alcohol and Substance-Related Mental Disorders
Primary: Change in Alcohol Use Disorders Identification Test (AUDIT) Score — -12.6; -8.1; -13.8; -10.3 score on a scale
Phase 4 N=86 Comparing Effectiveness of Duloxetine and Desipramine in Patients With Chronic Pain: A Pragmatic Trial Using Point of Care Randomization
Chronic Pain
Primary: Pain Intensity — 11; 29 Participants
Phase 2 N=43 Women's MoonShot: Neoadjuvant Treatment With PaCT for Patients With Locally Advanced TNBC
Stage I Breast Cancer AJCC v7 · Stage IA Breast Cancer AJCC v7 · Stage IB Breast Cancer AJCC v7
Primary: Number of Participants With Residual Disease — 24 Participants
N/A N=58 UrApp for Childhood Nephrotic Syndrome Management (Incident Cohort)
Idiopathic Nephrotic Syndrome
Primary: Number of Participants Reporting Medication Adherence — 25; 21; 19; 18 Participants
N/A N=80 Treatment Phenotypes for Adolescents With Asthma
Asthma in Children · Adherence, Treatment
Primary: Treatment Phenotypes — 7; 2; 10; 5 Participants
N/A N=13 Cranial Electrotherapy Stimulation: Piloting a Road to PTSD Prevention in First Responders
Adults
Primary: Feasibility of Cranial Electrotherapy Stimulation — 86.15 percentage of CES sessions completed
N/A N=110 Comparison of Pulmonary Vein Ablation With or Without Left Atrial Posterior Wall Ablation for Persistent AF (PIVoTAL)
Atrial Fibrillation Chronic · Persistent Atrial Fibrillation
Primary: 1-year Freedom From Recurrent Atrial Arrhythmias — 25; 14 Participants
N/A N=45 Radical RADiotherapy and Immunotherapy for Metastatic CAncer of the Lung (RRADICAL)
Stage IV Non-Small Cell Lung Cancer
Primary: Progression-free Survival — 26 Participants — p=0.0007
N/A N=320 Cryoballoon PVI With PWI Versus PVI Alone In Patients With PAF
Paroxysmal Atrial Fibrillation
Primary: Number of Participants With Recurrent Atrial Fibrillation — 60; 31 Participants
Phase 3 N=209 Lunsayil 1: A Study to Test Whether Spesolimab Helps People With a Skin Disease Called Hidradenitis Suppurativa
Hidradenitis Suppurativa
Primary: Part 1 - Percent Change From Baseline in Draining Fistula/Tunnel (dT) Count at Week 8 — -21.5; -41.9; -39.3; -25.8 Percentage change — p=0.697
N/A N=14 Open Pilot Trial of a Mind-body Program for Cardiac Arrest Survivors and Their Caregivers
Emotional Distress · Cardiac Arrest
Primary: Recruitment Feasibility Assessed by the Number of Eligible Dyads Enrolled — 7 dyads
N/A N=30 Social Support Intervention for Addiction Recovery
Alcohol; Harmful Use · Alcohol
Primary: Recruitment Feasibility — 10 participants per month
Phase 3 N=620 Clinical Trial of Iclepertin Effect on Cognition and Functional Capacity in Schizophrenia (CONNEX-1)
Schizophrenia
Primary: Change From Baseline in Overall Composite T-score of the Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Cognitive Battery…
N/A N=66 Care Coordination System for People With Dementia
Alzheimer Disease · Dementia · Dementia Alzheimers
Primary: Change in Baseline Burden and Stress of Caregivers Over 3 Months — -52.0; -31.9 percentage change