12,372 trials
Sturge-Weber Syndrome
Primary: Change in Cognitive Function as Assessed by the National Institute of Health (NIH) Toolbox Cognitive Battery — 44.2; 42.3; 34.1; 35.2 T score
Chronic Cough
Primary: Number of Participants Who Experienced at Least One Adverse Event (AE) — 79; 82 Participants
Atopic Dermatitis
Primary: Subjects With Investigator's Global Assessment (IGA) Score of 0 (Clear) or 1 (Almost Clear) at Week 16 — 17; 21; 4 Participants — p=0.002
Postoperative Pain
Primary: Sum of the Pain Intensity Differences (SPID) Over 24 Hours — 577.0; 563.2; 28.0 mm*hours — p=<0.0001
Cocaine Dependence
Primary: Cocaine Use Days as Measured by Self-report, Corroborated by Thrice-weekly Urine Drug Screens — 6.6; 7.2; 7.7 days of cocaine use
CKD Anemia in Stable Dialysis Patients
Primary: US (FDA) Submission: Mean Hb Change From Baseline to The Average Level During The Evaluation Period (Weeks 28 to 52), Regardless of Rescue Therapy — 10.30; 10.31; 0.39…
Migraine
Primary: Number of Subjects With at Least One Treatment-emergent Adverse Event (TEAE) — 18; 26 Participants
Small-cell Lung Cancer
Primary: Overall Survival (OS) — 8.6; 7.6 months — p=0.9029
Vitreomacular Traction
Primary: Proportion of Eyes With Central Vitreomacular Traction Release Without Rescue Vitrectomy — 78; 9 percentage of eyes
Osteosarcoma
Primary: The Number of Outpatient High Dose Methotrexate Courses Which Result in an Inpatient Hospital Admission. — 0 courses of MTX
Hepatitis C Virus Infection
Primary: Percentage of Participants With Sustained Virologic Response (SVR) < Lower Limit of Quantification (LLOQ) 12 Weeks After Discontinuation of Study Treatment — 98.1; 100…
Hemophilia A · Severe Hemophilia A
Primary: Incidence of Inhibitor Formation to FVIII in Previously Treated Patients (PTPs) With 100 Exposure Days (EDs) to CSL627 — 0 percentage of paticipants
Postoperative Pain
Primary: Mean Area Under the Curve (AUC) of the Numeric Rating Scale (NRS) Pain Intensity Scores With Activity (NRS-A) Through 72 Hours Postsurgery (AUC0-72), Compared With…
Postoperative Pain
Primary: Mean Area Under the Curve (AUC) of the Numeric Rating Scale (NRS) Pain Intensity Scores With Activity (NRS-A) Through 72 Hours Postsurgery (AUC0-72), Compared With…
Atopic Dermatitis
Primary: At Least 75% Reduction in Eczema Area and Severity Index (EASI75) From Week 0 to Week 16 — 64.2; 50.5 Percentage of responders — p=0.018