Phase 4 N=220 Corticosteroids for Acute Migraine in the Emergency Department
Migraine
Primary: Headache Days as Self-reported by Participants — 3.0; 3.3 days
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=65 Long-term Safety and Efficacy of Empagliflozin as Add on to GLP-1 RA
Diabetes Mellitus, Type 2
Primary: Percentage of Patients With Drug-related Adverse Events (AEs) During 52 Weeks of Treatment — 9.4; 21.2 Percentage of participants
Phase 4 N=135 Study of Efficacy of Ranibizumab in Different Regimens in Patients With Diabetic Macula Edema
Diabetic Retinopathy
Primary: Mean Average Change From Baseline in Best Corrected Visual Acuity (BCVA) of the Study Eye From Month 1 to Study Treatment Completion (Month 12) — 67.4; 65.1; 73.5; 73.8…
Phase 4 N=300 Study to Evaluate the Safety of 1 New 6:2 Influenza Virus Reassortant in Adults for the 2017-2018 Season
Influenza · Healthy
Primary: Percentage of Participants With Fever Greater Than or Equal to (>=) 101 Degrees Fahrenheit (F) — 0; 0 Percentage of Participants
Phase 4 N=31 Preemie Tots: A Pilot Study to Understand the Effects of Prematurity in Toddlerhood
Preterm Birth · Child Development · Child Behavior
Primary: Child Behavior - Pervasive Developmental Disorders Screening Test-II Stage 2 — -1.0; -0.2 score on a scale — p=0.67
Phase 4 N=50 Physiological and Psychological Effects of Testosterone During Severe Energy Deficit and Recovery
Caloric Restriction · Exercise
Primary: Body Composition at the End of Each Study Phase — 78.3; 78.0; 73.3; 75.8 kilograms
Phase 4 N=20 Clinical Trial to Evaluate Biafine Cream Versus Standard Care in Subjects With Actinic Keratosis Post Cryotherapy
Actinic Keratosis
Primary: Mean Severity Score — -1.52; -1.80 units on a scale
Phase 4 N=36 Impact of Combined Hormonal Contraceptives on UPA
Contraception
Primary: Number of Participants With Follicle Rupture — 1; 9 Participants
Phase 4 N=87 A Study of The Effect of Altitude on Mircera (Methoxy Polyethylene Glycol-Epoetin Beta) Dose Requirements in Participants With Chronic Renal Anemia in Pre-Dialysis or Dialysis
Anemia, Kidney Disease, Chronic
Primary: Mean Dose Required to Achieve Target Hemoglobin of 11-12 g/dL — 150.3; 194.7; 98.7; 66.6 micrograms (mcg)
Phase 4 N=68 Efficacy of IV Acetaminophen for Pain Management
Post-operative Pain
Primary: Opioid Rescue - 48 Hours — 54.4803; 48.9253 Milligrams of intravenous morphine equiv — p=.356
Phase 4 N=36 Tocilizumab as Add-On Treatment For Residual Positive, Negative, and Cognitive Symptoms of Schizophrenia
Schizophrenia · Schizoaffective Disorder
Primary: Clinical Response to Tocilizumab — -5.33; -0.5 Units on a scale (PANSS)
Phase 4 N=40 MI Varnish and MI Paste Plus in a Caries Prevention and Remineralization Study
Dental White Spots · Dental Caries
Primary: Change in White Spot Lesions Count - Enamel Decalcification Index (EDI) — 40.2; 41.3 units on a scale
Phase 4 N=649 Postmarketing Study to Evaluate add-on Therapy With Anticholinergics in Patients With Overactive Bladder (OAB) on Mirabegron.
Overactive Bladder (OAB)
Primary: Number of Participants With Treatment-Emergent Adverse Events (TEAEs) — 131; 135; 133; 120 Participants
Phase 4 N=72 Total Intravenous Anesthesia in Sinus Surgery
Advanced Chronic Rhinosinusitis
Primary: Intraoperative Visual Field Assessment — 3.3; 4.3; 3.3; 4.2 units on a scale
Phase 4 N=48 Symptom Response in Normal and Dry Eye Patients Secondary to Application of a Menthol-Containing Eyedrop (Rohto® Hydra)
Dry Eye
Primary: Sum of the Cooling Scale For Rohto (r) Hydra — 24.6; 12.1 units on a scale