N/A N=15 Early Changes In Multiparametric MRI In Prostate Cancer
Prostate Cancer
Primary: Correlation Between MRI Parameter at Visit 1 and Nadir PSA — -0.53 correlation coefficient — p=0.09
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=213 An Efficacy and Safety Study of Azacitidine Subcutaneous in Combination With Durvalumab (MEDI4736) in Previously Untreated Adults With Higher-Risk Myelodysplastic Syndromes (MDS) or in Elderly Patients With Acute Myeloid Leukemia (AML)
Leukemia, Myeloid, Acute · Myelodysplastic Syndromes
Primary: MDS Cohort: Overall Response Rate — 61.9; 47.6 percentage of participants — p=0.1838
Phase 2 N=100 Crushed Ticagrelor Versus Eptifibatide Bolus + Clopidogrel
Acute Coronary Syndrome · Angina, Unstable
Primary: Number of Participants With a Change in high-on Treatment Platelet Reactivity (HPR) — 37; 33; 24; 0 count of participants
Phase 3 N=258 A Study to Evaluate the Efficacy of Venetoclax Monotherapy in Relapsed/Refractory Participants With Chronic Lymphocytic Leukemia (CLL)
Chronic Lymphocytic Leukemia
Primary: Complete Remission Rate in Participants Not Previously Treated With BCRi Therapy - Primary Analysis — 35.1 percentage of participants — p=<0.001
N/A N=328 The STIC Norway RCT Study: Using Feedback in Psychotherapy.
Psychological Feedback
Primary: Beck Depression Inventory II — 15.10; 16.02; 10.78; 9.35 score on a scale — p=<0.05
N/A N=661 Single Embryo TrAnsfeR of Euploid Embryo
Infertility · Aneuploidy
Primary: Ongoing Pregnancy — 137; 143 Participants
Phase 2 N=14 Synergistic Pharmacologic Intervention for Prevention of ROP (SPIPROP Study)
Retinopathy of Prematurity
Primary: Efficacy as Measured by the Number of Participants Presenting With Retinopathy of Prematurity (ROP) and the Rate of Stages/Grade of ROP. — 5; 3; 4; 1 Participants
Phase 1 N=24 A Study of LY900014 Administered in Participants With Type 1 Diabetes Using an Insulin Pump
Diabetes Mellitus, Type 1
Primary: Pharmacokinetics (PK): Insulin Lispro Area Under the Concentration Curve From Time Zero to 5 Hours(h) (AUC [0-5 h]) Following Administration of Each Study Arm With a…
Phase 2 N=12 Chemotherapy and HAART to Treat AIDS-related Primary Brain Lymphoma
AIDS-Related-Primary Central Nervous System Lymphoma
Primary: Number of Patients Alive at 2 Years Without Recurrent Brain Lymphoma or Severe Neurocognitive Defects — 8 Participants
N/A N=369 Defining the Intestinal Microbiota in Premature Neonates
Premature Intestinal Microbiota · Necrotizing Enterocolitis · Late Onset Bloodstream Infection
Primary: The Composition of Bacteria Present, Established by Ultra-deep RNA Gene Sequencing, in Pre-morbid Faecal Samples From Neonates With Necrotizing Enterocolitis and…
Phase 1 N=49 A Study to Compare 2 Formulations of LY900014 in Healthy Participants
Healthy
Primary: Pharmacokinetics (PK): Insulin Lispro Area Under Plasma Concentration Curve Zero to 10 Hours (AUC[0-10]) — 1760; 1550 hours times picomols per milliliter
Phase 3 N=167 Study With Oral Ferric Maltol for the Treatment of Iron Deficiency Anemia in Subjects With Chronic Kidney Disease
Renal Insufficiency, Chronic · Iron-Deficiency Anemia
Primary: Change in Hb Concentration From Baseline to Week 16 — 0.50; -0.02 g/dl — p=0.0149
N/A N=40 Effectiveness of a Preoperative Pulmonary Rehabilitation Program in Patients Awaiting Lung Resection
Lung Cancer
Primary: Exercise Tolerance — 459.7; 341 Seconds
N/A N=4 Novel Brain Signal Feedback Paradigm to Enhance Motor Learning After Stroke
Stroke
Primary: Arm Motor Abilities Test Functional Domain (AMAT - F) — .54 units on a scale
N/A N=36 Analysis of Orthodontic Tooth Movement Using 3D Imaging
Tooth Crowding · Dental Crowding · Malocclusion
Primary: Change in Little's Index From Baseline to 6 Weeks — -2.5; -2.9; -2.3; -2.6 mm