6,678 trials
Influenza · Healthy
Primary: Percentage of Participants With A/H1N1 Hemagglutination Inhibition (HAI) Antibody Seroconversion Rate at Day 28 — 10.0; 5.4; 23.4 Percentage of participants — p=0.006
Diabetes Mellitus, Type 2 · Albuminuria
Primary: Progression of Albuminuria — 153.01; 99.80 Events per 1000 patient-year — p=<.0001
Ureterolithiases
Primary: Proportion of Patients Passing Their Stone Within 28 Days by Self Report — 128; 113 Participants
Rheumatoid Arthritis
Primary: Remission According to DAS28-CRP at Week 16 — 69; 72; 61; 25 Participants
Type 2 Diabetes Mellitus
Primary: Changes From Baseline in the Standard Deviation (SD) of 24-hour Blood Glucose Values — -7.51; -13.04; -11.76; -15.24 mg/dL
Multiple Sclerosis
Primary: Diffusion and Myelin Fraction Water Changes on Magnetic Resonance Imaging (MRI) — -2.06 percent Change
Single Ventricle Heart Disease After Fontan Surgery
Primary: End-systolic Elastance — 0.85; 1.8 Ees in mmHg/ml/m2
Diarrhea Rotavirus
Primary: Number/Percentage of Subjects With Seroconversion for Anti-measles Immunoglobulin G (IgG) Antibody — 246; 255; 2; 3 Participants
Prehypertension · Hypertension
Primary: Systolic Blood Pressure — 144; 126; 140; 125 mmHg
COPD · Chronic Obstructive Pulmonary Disease · Moderate to Very Severe COPD
Primary: Rate of Moderate or Severe Chronic Obstructive Pulmonary Disease (COPD) Exacerbations Per Subject Per Year During the First Year of Treatment — 0.44; 0.57 Events per…
Blood Loss · Hip Arthritis · Knee Arthritis
Primary: Total Blood Loss Over Course of Stay (Intraoperative and Postoperatively Until Discharge) — 934.1; 948.7; 660.6; 891.2 milliliters — p=<0.05
Acute Pain
Primary: Total Opioid Use for Pain Control — 20.8; 25.0 mg Morphine equivalents
Chronic Obstructive Pulmonary Disease, COPD
Primary: Change in Left Ventricular End-diastolic Volume (LVEDV) — 11.873; -0.954 ML — p=<0.0001
Immunity to Oral Rotavirus Vaccine · Immunity to Oral Polio Vaccine · Shedding of Oral Rotavirus Vaccine
Primary: Number/Percentage of Subjects With Immune Response to Rotavirus Vaccine — 54; 40; 42; 37 Participants
Rheumatoid Arthritis
Primary: Baseline to Month 3 Change in Total Power Doppler Synovitis Score of 34 Joints (Range 0 - 102) — 6.84 units on a scale