Phase 4 N=27 Dexamethasone Plus Virtual Reality Exposure Therapy for PTSD
PTSD
Primary: Change in The Clinician Administered PTSD Scale (CAPS)Scores — -11; -15.22 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=101 Potential Mechanisms for Intussusception After Rotavirus Vaccine-Pilot Study
Intussusception · Rotavirus Infections
Primary: The Effects of RV1 and RV5 With or Without Other Routine Immunizations on Gastrointestinal Anatomy — 2; 1; 0; 1 Participants — p=0.2
Phase 4 N=110 Perioperative Gabapentin Use In Head And Neck Mucosal Surgery Patients
Head and Neck Cancer · Acute Pain · Postoperative Pain
Primary: Change in Daily Narcotic Consumption — 1.60; 1.59 mg/hour
Phase 4 N=305 Preventing Relapse in Schizophrenia: Oral Antipsychotics Compared To Injectables: Evaluating Efficacy
Schizophrenia · Schizoaffective Disorder
Primary: Substantial Clinical Deterioration Measured by Psychotic Symptoms — 1.8; 2.0 units on a scale
Phase 4 N=46 Oral Contraceptives, Insulin Resistance and Cardiovascular Risk Profile in Pre-Menopausal Women
Insulin Sensitivity · Cardiovascular Risk · Perimenopausal Disorder
Primary: Change From Baseline in Insulin Sensitivity — -1.91; -5.63 min ^ -1 / mIU / L
Phase 4 N=304 A Study of Duloxetine (LY248686) in Participants With Diabetic Peripheral Neuropathic Pain (DPNP)
Diabetic Peripheral Neuropathic Pain
Primary: Change From Baseline to 12 Weeks in the Weekly Mean of the 24-Hour Average Pain Score on the 11-Point Numeric Rating Scale (NRS) — -2.358; -2.286 units on a scale…
Phase 4 N=8 Post-meal Insulin Dosing With Adjuvant Pre-meal Pramlintide in Children With Type 1 Diabetes Mellitus
Type 1 Diabetes Mellitus
Primary: Assess the Mean Area Under the Curve (AUC) for Blood Glucose Concentration in Subjects Treated With Pramlintide + Insulin, Compared to Insulin Alone — 205; 993 mmol*L/min
Phase 4 N=8 Single Dose Population Pharmacokinetics of Intravenous Posaconazole in Critically Ill Patients
Systemic Fungal Infections
Primary: Posaconazole Exposure Described as Area Under the Total Plasma Concentration-time Curve From Time Zero to Infinity After a Single Dose — 17932 ng*h/mL
Phase 4 N=140 Effect of Dexmedetomidine on Emergence Agitation in Children With or Without Tube Insertion Under General Anesthesia
Myringotomy
Primary: Participant's Severity of Emergent Agitation (EA) Using the Pediatric Anesthesia Emergence Delirium (PAED) Scale in PACU (Post-Op Area). — 7; 8 units on a scale
Phase 4 N=58 D-Cycloserine Augmentation of Cognitive Behavioral Therapy for Delusions
Schizophrenia · Schizoaffective Disorder · Delusional Disorder
Primary: Change in Psychotic Symptoms Rating Scale-Delusions (PSYRATS-D) — 14.26; 11.83; 12.18; 11.91 units on a scale
Phase 4 N=402 Patient Assisted Intervention for Neuropathy: Comparison of Treatment in Real Life Situations
Cryptogenic Sensory Polyneuropathy
Primary: Co-Primary Measures: Percent of Patients With at Least a 50% Decrease in Likert Pain Scale From Baseline to Week 12 Follow Up and Percent of Patients That Quit — 34; 29…
Phase 4 N=80 A Prospective Analysis of Preoperative Fascia Iliaca Block for Hip Arthroscopy
Muscle Weakness | Patient · Pain
Primary: Numeric Pain Score — 7; 6 units on the numeric rating scale (0-10)
Phase 4 N=160 Analgesia Duration of Dexamethasone, Buprenorphine, or Clonidine With Ropivacaine for Interscalene Nerve Block
Anesthesia, Local
Primary: Duration of Analgesia — 911; 1026.5; 1181; 982 minutes
Phase 4 N=302 Linagliptin as Add on to Basal Insulin in the Elderly
Diabetes Mellitus, Type 2
Primary: Change From Baseline in Hemoglobin A1c (HbA1c) After 24 Weeks of Treatment. — -0.38; -1.01 Percentage (%) of HbA1c — p=< 0.0001
Phase 4 N=20 Effects of Antidiabetic Medications on the Postprandial State in Prediabetes
Prediabetes · Obesity
Primary: Monocyte NfkB Levels as Detected by Western Blotting — 62.79; 72.03; 67.68; 84.19 NfkB p65 arbitrary units