65,437 trials
HIV-1 Infection
Primary: Percentage of Participants With HIV-1 RNA < 50 Copies/mL at Week 24 as Defined by the Food and Drug Administration (FDA)-Defined Snapshot Algorithm — 97.7 percentage of…
Optical Coherence Tomography (OCT) of the Retina
Primary: Number of Participants With Acceptable OCT Image Quality — 60 Participants
Duchenne Muscular Dystrophy
Primary: Number of Participants With Adverse Events Related to AVI-4568 — 0; 0 Participants
Visual Acuity
Primary: Overall Comfort Score — 64.7; 62.6 Units on a Scale
Severe Hemophilia A
Primary: Number of Participants Who Developed Target Joint Bleeding — 17 Participants
Dental Devices, Home Care
Primary: Whole-mouth Mean Modified Gingival Index (MGI) Score at Day 42 — 1.880; 1.770 Unit on a scale
Tobacco Use Disorder
Primary: Assessment of Bioequivalence of Prototype Mini Lozenges With Nicorette Mini Lozenge by Measuring Area Under the Plasma Concentration Versus Time Curve From Time Zero to…
EMBRYO IMPLANTATION
Primary: Positive Pregnancy Test — 112; 113 Participants
Allergic Rhinitis
Primary: Total Nasal Symptom Score After Nasal Allergen Challenge (NAC) — 3.37; 4.71 score on a scale — p=<0.05
Retinitis Pigmentosa · AMD
Primary: Rod Sensitivity Within the Central Retina as Measured on the Nidek MP-3S — 7; 20 Participants — p=<0.05
Chronic Kidney Disease
Primary: Patient Activation Measure (PAM) -13 Item Questionnaire — 9.1; -1.4 points — p=0.01
Macular Edema
Primary: Mean Change From Baseline in Best Corrected Visual Acuity (BCVA) at Week 52 — 0.4; 0.5; 1.7 Scores on a scale — p=<0.0001
Coma · Heart Arrest · Anoxia
Primary: Rate of Awakening (Number of Patients Who Are Able to Follow Commands) — 2; 2 Participants
Rheumatoid Arthritis
Primary: Double Blind Phase: Change From Randomization in Disease Activity Score in 28 Joints Using 4 Variables (DAS28-4) (Erythrocyte Sedimentation Rate [ESR]) at Week 48…
Hypertension
Primary: Change in Blood Pressure — -1; -2; -2; -2 mmHg