65,437 trials
Small Cell Lung Cancer
Primary: Objective Response Rate — 15.5; 14.6; 19.3; 18.8 percentage of participants
Chronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP)
Primary: Change From Baseline at Week 24 in Nasal Congestion/Obstruction Symptom Severity Score — -0.38; -1.25 score on a scale — p=<0.0001
Hyperemia
Primary: Number of Participants With Treatment Emergent Adverse Events (TEAEs) — 66; 38; 44; 25 Participants
Onychomycosis
Primary: Primary Endpoint - Efficacy — 4 Participants
Alcohol Use Disorder
Primary: Corticolimbic Functional Connectivity Based on fMRI Blood Oxygenation Level Dependent (BOLD) Response During the Stress Versus Neutral Conditions of the Montreal Imaging…
Advanced Dementia
Primary: Documented Decisions to Forgo Hospitalization — 133; 119 Participants
Ebola Virus
Primary: Number of Participants With One or More Solicited Local Treatment-Emergent Adverse Events (TEAE) — 8; 8; 10; 3 Participants
Neoplasms · Neoplasm Metastasis
Primary: Recommended Phase 2 Dose of LY3164530: Maximum Tolerated Dose (MTD) — 1000; 500 milligrams (mg)
Assess Phenylephrine on EVP and IOP
Primary: Change in Episcleral Venous Pressure (EVP) — 7.2 mmHg — p=<0.01
Pneumococcal Infections
Primary: Percentage of Participants Achieving the Serotype-specific Pneumococcal Immunoglobulin G (IgG) Antibody Threshold Value of ≥0.35 µg/mL for the 13 Common Serotypes in…
Obesity
Primary: Stress-induced Overeating Measured Via Smartphone Surveys — 0.74; 0.55 episodes
PTSD
Primary: Change in PTSD Checklist for DSM-5 (PCL-5) Scores Over 4 Weeks of Treatment — 15.11; 2.50 units on a scale
Osteoarthritis
Primary: Change at 6 Months From Baseline in First Peak Knee Adduction Moment (KAM): (6 Month Value - Baseline) — -0.19 %Bw*Ht
Irritable Bowel Syndrome
Primary: Percentage of Participants Who Were Composite Responders Based on Improvements From Baseline in Daily Worst Abdominal Pain and Daily Stool Consistency Scores at Week 4…
Osteoarthritis of the Knee
Primary: Pain When Walking On A Flat Surface — 0; 1; 8; 4 Participants