Phase 1 N=6 Open Label, Adaptive, Parallel Group PET Study Using RO7017773 And [11C] RO15-4513
Autism Spectrum Disorder
Primary: Percentage of Brain Alpha5-Containing GABA-A Receptors Occupied by RO7017773
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=306 Effectiveness and Handling of Spiolto® Respimat ® in COPD Patients - Italy
Pulmonary Disease, Chronic Obstructive
Primary: Percentage of Patients With Therapeutic Success at Week 6 Approximately (Approx.) (Visit 2) — 52.52 Percentage of Participants (%)
N/A N=21 Observational Clinical Study to Plan, Position and Check Instrument Placement for Spine Surgery Interventions
Spinal Diseases
Primary: Clinical Accuracy of Pedicle Screw Placement Using New Image-guidance Software — 94.1 Percentage of screw placements
Phase 3 N=3,043 Efficacy and Safety of Low-dose Ticagrelor
Coronary Artery Disease
Primary: ADP-induced Inhibition of Platelet Aggregation — 54.9; 80.6; 73.6; 66 percentage of inhibition of platelet agg
Phase 4 N=5 Tolerability of Suprascapular and Median Nerve Blocks for the Treatment of Shoulder-hand Syndrome
Shoulder Hand Syndrome · Complex Regional Pain Syndromes
Primary: Number of Participants Demonstrating Tolerability of Suprascapular and Median Nerve Blocks — 5 Participants
N/A N=634 Transabdominal and Transvaginal Sonography in Medical Abortion
Abortion Early
Primary: Percentage of Subjects in Each Ultrasound Group With Additional Testing — 63; 14 Participants
Phase 4 N=65 Safety and Efficacy of Azzalure/Dysport, Restylane/Emervel Filler and Restylane Skinbooster Treatment
Aesthetics
Primary: Percentage of Subjects With Improvement in Global Facial Aesthetic Appearance — 66.7; 93.5 percentage of subjects
Phase 4 N=137 Nicotine Replacement for Smoking Cessation During Pregnancy
Nicotine Dependence · Smoking Cessation
Primary: Number of Participants Who Self Report an Average of Zero Cigarettes Smoked Per Day in Preceding 7 Days — 12; 7 Participants
Phase 3 N=615 Evaluation of Alirocumab Versus Ezetimibe on Top of Statin in Asia in High Cardiovascular Risk Patients With Hypercholesterolemia
Hypercholesterolemia
Primary: Percent Change From Baseline in Calculated Low Density Lipoprotein Cholesterol at Week 24: Intent-to-treat (ITT) Analysis — -20.3; -56.0 percent change — p=<0.0001
N/A N=18 Immune Dysfunction in Allergic Asthma
Asthma
Primary: Anti-KLH Antibody. This is Measured by ELISA and Expressed as ELISA Units Which Are Derived by Dilution of Serum Samples Until the Result Falls on a Linear Portion of…
N/A N=280 Motivational Coaching to Enhance Mental Health Engagement in Rural Veterans
Mental Health · Rural Health · Veterans Health
Primary: Mental Health (MH) Treatment Engagement — 78; 74 Participants — p=0.660
Phase 3 N=499 Minimally Invasive Surgery Plus Rt-PA for ICH Evacuation Phase III
Intracerebral Hemorrhage
Primary: Dichotomized, Adjudicated Modified Rankin Scale Score 0-3 vs. 4-6 at 365 Days Post Ictus (Adjusted) — 110; 100; 139; 140 Participants — p=0.73
Phase 4 N=70 Combined Letrozole and Clomid in Women With Infertility and PCOS
Polycystic Ovary Syndrome · Infertility
Primary: Number of Participants Achieving Ovulation Measured by Mid-luteal Progesterone Level — 15; 27 Participants — p=0.007
N/A N=10 Effect of Symbicort on GR Localisation in Asthma
Asthma
Primary: Changes in GR-GRE Binding — 1.4; 1.4; 1.6; 2.3 GRE activity (OD) — p=0.04
N/A N=11 Memantine to Reduce Neurocognitive Deficits Following Unilateral ECT for the Treatment of a Major Depression
Depressive Disorder, Major
Primary: Memantine Effect on CVLT Long Term Recall After Right Unilateral ECT Treatment. — 10.17; 6.67 units on a scale — p=0.006