Phase 4 N=30 Combining Lovastatin and a Parent-Implemented Language Intervention for Fragile X Syndrome
Fragile X Syndrome · Genetic Diseases
Primary: Expressive Language Sample Composite Score in the Home — 39.63; 42.47 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=19 Drug Exposure Registry for GSK2248761, an Investigational NNRTI
HIV Infections
Primary: Number of Participants With Occurrence of Seizure — 0; 1 Participants
Phase 2 N=20 Autologous, Micro-fragmented Adipose Tissue for Meniscal Tears
Tibial Meniscus Injuries · Osteoarthritis, Knee
Primary: Change in Numerical Pain Scale — -3.2 units on a scale
Phase 4 N=86 Pharmacoeconomics and Related Patient Outcomes of Multi-dose Intravenous Acetaminophen (OFIRMEV)
Prostatectomy · Pain
Primary: Post Anesthesia Care Unit Length of Stay — 124; 132 minutes
Phase 4 N=57 Belatacept Compared to Tacrolimus in Deceased Donor Renal Transplant Recipients
Implant or Graft; Rejection
Primary: Number of Participants With Delayed Graft Function (DGF) — 12; 15 Participants
N/A N=7 The Set-Point Study for Type 2 Diabetes: Evaluating the Use of an Insulin Only Bionic Pancreas System in Type 2 Diabetes
Type 2 Diabetes Mellitus
Primary: Mean Dexcom CGM Glucose (CGMG) Level — 152.8; 137.1 mg/dl
Phase 2 N=33 Hemodynamics and Extravascular Lung Water in Acute Lung Injury
Acute Lung Injury
Primary: The Primary Efficacy Variable Will be the Total Reduction in Measured Lung Water
N/A N=13 Circumferential Periareolar Mastopexy Using SERI Surgical Scaffold
Mastopexy
Primary: Number of Participants With Areolar Dilation of up to 6mm at 12 Months — 13 Participants
Phase 2 N=78 Study of the Combination of ACP-196 and Pembrolizumab in Subjects With Platinum Resistant Urothelial Bladder Cancer
Metastatic Urothelial Carcinoma
Primary: Number of Participants With Overall Response — 9; 8 Participants
Phase 3 N=160 Music vs Midazolam During Preop Nerve Block Placement
Anxiety · Peripheral Nerve Block
Primary: Anxiety Levels — 33.3; 30; 30; 23.3 score on a scale
Phase 4 N=10 Transdermal Patch CVD 2000: The Effect of Heat on Fentanyl Release From Fentanyl TDSs in Healthy Adults
Peer Review, Research
Primary: Partial Area Under the Curve (AUC) Attained With Early and Late Heat in Each of the Three Fentanyl TDSs (Reference and Generic) — 2.2; 1.7; 2.1; 2.7 h*ng/mL
Phase 2 N=578 Safety and Efficacy Study of GDC-0853 Compared With Placebo and Adalimumab in Participants With Rheumatoid Arthritis (RA)
Rheumatoid Arthritis
Primary: Percentage of Participants Achieving American College of Rheumatology 50% (ACR50) Response at Day 84, Comparison Between GDC-0853 and Placebo (Cohort 1) — 17.5; 27.5…
Phase 3 N=89 Pembrolizumab Plus Epacadostat, Pembrolizumab Monotherapy, and the EXTREME Regimen in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (KEYNOTE-669/ECHO-304)
Head and Neck Cancer
Primary: Objective Response Rate (ORR) of Pembrolizumab + Epacadostat, Pembrolizumab Monotherapy and the EXTREME Regimen — 31.4; 21.1; 34.3 percentage of participants
N/A N=200 Detection of SLN in Patients With Endometrial Cancer Undergoing Robotic Assisted Staging: Comparison of ISB and ICG
Endometrial Cancer
Primary: Number of Pelvic Sentinel Lymph Nodes (SLN) in Endometrial Cancer Patients Detected by Either ICG and/or ISB Dyes. — 1.25; 2.03 nodes
Phase 4 N=50 Cost Comparison Study of Darbepoetin Versus Epoetin Therapy to Treat Anemia in Hemodialysis Patients
Anemia · Chronic Kidney Disease
Primary: Cost of Erythropoiesis Stimulating Agent — 4178.70; 2302.92 dollars Canadian