Phase 3 N=91 Contact Lenses With New UV-blocker Manufactured With Different Techniques
Correction of Refraction Error · Attenuation of Bright Light
Primary: Overall Comfort Score — 61.49; 67.27 Units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=207 Extended Varenicline Treatment for Smoking Among Cancer Patients
Nicotine Dependence
Primary: 7-day CO-verified Tobacco Abstinence — 28; 32; 16; 17 participants
Phase 4 N=46 Comparison of the Cognitive and Behavioral Effects of Eslicarbazepine Acetate and Carbamazepine in Healthy Adults
Epilepsy
Primary: Overall Composite Z Score of Neuropsychological Battery as a Measure of Direct Comparison of the 2 Antiepileptic Drugs. — .001; -.23 Z-score — p=< .001
Phase 3 N=718 Double-masked Study of PG324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension
Open-angle Glaucoma · Ocular Hypertension
Primary: Intraocular Pressure (IOP) — 24.84; 24.81; 24.59; 23.72 mmHg — p=<0.0001
Phase 2 N=34 Pharmacokinetics (PK)/Safety Study of Atorvastatin in Children With Kawasaki Disease and Coronary Artery Abnormalities
Kawasaki Disease
Primary: Number of Participants With SAE — 4 Participants
Phase 4 N=100 Efficacy of Optison Echo Contrast to Detect Thrombus in Left Atrial Appendage
Atrial Fibrillation
Primary: Percent Confidence in Assessment of Left Atrial Appendage Thrombus — 55; 95 Percentage of Confidence — p=< 0.001
Phase 4 N=11 Pharmacokinetics of Tedizolid Phosphate in Cystic Fibrosis
Cystic Fibrosis
Primary: Peak Plasma Concentration (Cmax) — 2.22; 2.92 mg/liter
N/A N=34 Robotic Brace Incorporating Electromyography for Moderate Affected Arm Impairment After Stroke
Hemiparesis
Primary: Impairment in the Affected Upper Extremity as Measured by the Fugl Meyer Scale. — 19.6; 18.0; 17.6 units on a scale
N/A N=47 Evaluation of an Ascensia Diabetes Care Blood Glucose Meter and App System
Diabetes Mellitus
Primary: Percent of Responses From Persons With Diabetes That 'Strongly Agree' or 'Agree' or 'Neither Agree Nor Disagree' With Questionnaire Statements Regarding Success With…
N/A N=35 Evaluation of Changes to Skin Microbiome With Tape-Stripped Wounds
Healthy Volunteers
Primary: Microbial Community Richness - Baseline (Day 0) — 56.5862069; 32.13043478; 43.72413793; 34.03703704 Number of bacterial taxa — p=0.071225
Phase 2 N=298 Study Assessing Safety and Efficacy of PG324 Ophthalmic Solution in Patients With Elevated Intraocular Pressure
Open Angle Glaucoma · Ocular Hypertension
Primary: Intraocular Pressure (IOP) — 25.11; 25.12; 25.35; 25.99 mmHg — p=<0.0001
Phase 2 N=169 Safety and Efficacy of Varying Regimens of CANDIN for Treatment of Common Warts (Verruca Vulgaris)
Warts
Primary: Number of Subjects With Complete Resolution of a Primary Injected Wart(s) at Any Treatment or Follow-up Visit — 16; 29; 31; 29 Participants — p=0.0329
N/A N=302 Harnessing the Power of Text Messaging to Invigorate AMSM HIV Preventive Behavior
HIV
Primary: The Number of Condomless Sex Acts at 3-months Post-intervention — 2.85; 2.73 number of unprotected sex acts
Phase 2 N=18 Buprenorphine Used With Treatment Resistant Depression in Older Adults
Major Depressive Disorder · Depression
Primary: Montgomery-Asberg Depression Rating Scale (MADRS) — -1; -5.3; 21.3; 15.3 units on a scale
N/A N=29 Study to Assess the Cosmetic Changes in the Facial Skin After Use of a Topical Retinoid Product in Participants With Moderate to Severe Photodamage
Skin Care
Primary: Change From Baseline in Overall Photodamage Score — 5.6; -0.8 score on a scale — p=<0.001