17,261 trials
COVID-19
Primary: Proportion of Participants Alive and Without Mechanical Ventilation Through Day 29 in Participants With Baseline Ordinal Score of 5 or 6, C-reactive Protein…
Parkinson Disease Psychosis
Primary: Change From Double Blind (DB) Baseline in Total Scale for Assessment of Positive Symptoms - Parkinson's Disease ( SAPS-PD) Score at Week 6 — -1.4; -2.5 Units on a scale
Infantile Spasms
Primary: Change From Baseline in Frequency of Spasm Clusters at Day 10 — 1.0; 2.7; -5.4; -1.0 Spasm clusters per day — p=0.7391
Myasthenia Gravis
Primary: Percentage of Participants With Treatment Emergent Adverse Events (TEAEs), Serious Adverse Events (SAEs), Grade 3 or Higher TEAEs, and Adverse Event (AE) Leading to…
Alcohol Use Disorders (AUD)
Primary: Number of Participants Experiencing Adverse Events in the Mifepristone Versus Placebo Group as a Measure of Safety and Tolerability — 0; 3 Participants — p=>.05
Glioma · High Grade Astrocytoma · Glioblastoma Multiforme
Primary: Number of Participants Experiencing the Incidence of Grade One or Higher Adverse Events — 12 participants
HIV-1-infection
Primary: The Percentage of Participants With Grade 3 or Higher Treatment-related Adverse Events — 0; 0; 0; 0 Participants
Acne Vulgaris
Primary: Absolute Change in Inflammatory Lesion Counts — -7.7; -4.1; -11.2; -11.3 inflammatory acne lesions
Non-Small Cell Lung Cancer
Primary: Disease Response (RECIST) — NA days
Type 2 Diabetes Mellitus · Obese · Overweight
Primary: Change in Postprandial Glucose — -2803; 629 mmol/6hr — p=<0.05
Hepatocellular Carcinoma
Primary: Overall Response Rate (ORR) Per RECIST 1.1 by Central Assessment — 5.9; 11.1; 7.4; 14.8 Percentage of participants
Covid19
Primary: For Viral Domain: Change in Viral Shedding — 1.6; 1.7; 1.0 cycles — p=0.20
Acute Myeloid Leukemia · Higher Risk Myelodysplastic Syndrome
Primary: Stage 1: Dosing Schedule of Low-dose Cyclophosphamide — 6; 6 Participants
Corneal Endothelial Cell Loss · Ocular Pain · Ocular Inflammation
Primary: Change From Baseline in Central Corneal Endothelial Cell Counts — -243.4; -184.8; -260.3 cells/mm^2 — p=0.4529
Ocular Hypertension · Primary Open Angle Glaucoma
Primary: Change From Baseline in Intraocular Pressure at Day 28 (Study Eye) — -6.95; -7.95; -7.04 mmHg — p=0.8070