65,437 trials
Capsule Endoscopy
Primary: Completion Rate (Rate at Which Small Bowel is Completely Examined) — 57 Participants
Psoriatic Arthritis
Primary: Percentage of Participants Simultaneously Achieving American College of Rheumatology 50 (ACR50) and Psoriasis Area and Severity Index 100 (PASI100) — 36; 27.9 percentage…
Polycythemia Vera
Primary: Number of Participants With Adverse Events - All Grades — 143; 26 Participants
Smoking Cessation · Smoking · Nicotine Dependence
Primary: Biochemically-confirmed 7-Day Point-Prevalence Abstinence at 26 Weeks — 63; 124; 108 Participants — p=.3623
Skin Care
Primary: Frequency of Combined Dermatologist Score — 1; 1; 51; 55 Participants
Psoriasis
Primary: The Mean Percent Change From Baseline to Week 12 in Psoriasis Area and Severity Index (PASI). — -25.08; -12.63 percent change — p=0.2205
Pneumococcal Infections
Primary: Percentage of Participants With an Adverse Event (AE) — 74.9; 72.3; 67.4 Percentage of Participants
Vulvovaginal Atrophy · Dyspareunia
Primary: Visible Changes to the Vulva, Vestibule and Vaginal Region on Photography — 8 points improvement on VGTA scale — p=0.05
Human Papilloma Virus Vaccines · Attitude to Health
Primary: Intention to Vaccinate Against HPV in the Next 12 Months — 3.49; 3.87; 4.16 score on a scale — p=<.02
Asthma
Primary: Change in Asthma Control Test Score — 3.32 change in composite score
Hypertension
Primary: Number of Participants With Treatment Related Adverse Events — 208 participants
Hysterectomy · Pain, Postoperative
Primary: Post-operative Pain: VAS — 4.1; 4.8 score on a scale — p=0.17
Sickle Cell Disease
Primary: Number of Participants With Successful Pain Interventions by Arm Between Presentation and 3 Hours Post Administration of Study Drug — 13; 17; 27; 25 Participants — p=0.227
Norovirus
Primary: Percentage of Participants With a Seroresponse (Pan-Ig ELISA) in Cohort 1 — 77.4; 63.5; 74.5; 85.7 percentage of participants
Osteoarthritis
Primary: Change From Baseline to Month 3 and Change From Baseline to 9 Month in Western Ontario and McMasters Universities Osteoarthritis (WOMAC) Pain Subscale — -1.59; -0.96…