N/A N=25 Comparative Effects of Nebivolol and Metoprolol on Female Sexual Function
Hypertension · Female Sexual Dysfunction
Primary: Change in Female Sexual Function Index — 1.24; 1.42 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=83 Pilot Study to Examine Health Effects of Daylight Exposure on Dementia Patients
Dementia · Depression · Behavior Disorders
Primary: Change in Cornell Scale for Depression in Dementia (CSDD) — 1.5; -2.0 units on CSDD scale — p=0.01
Phase 1 N=16 Effect of Multiple Doses of Itraconazole on the Pharmacokinetics of a Single Oral Dose of BI 1026706 in Healthy Male Subjects
Healthy
Primary: Area Under the Curve of BI 1026706 From 0 to the Last Quantifiable Data Point (AUC0-tz) — 921; 1580 nmol*h/L
N/A N=966 Supplement to Hospital to Home Outcomes
Hospitalized Patients
Primary: Number of Participants With Any Occurrence of Unplanned Re-hospitalization and/or Any Emergency/Urgent Care Visits Within 30 Days of Hospital Discharge — 77; 63…
Phase 2 N=68 A Study to Evaluate the Clinical Effect of Daily Next Science™ Acne Gel (NAG) on Mild to Moderate Facial Acne
Acne Vulgaris
Primary: Change in Inflammatory Lesions With Daily Use of NAG Compared With Vehicle After 12-weeks of Use. — -27; -44 % change of inflammatory lesions count — p=<0.01
Phase 1 N=12 Safety Study of Local Administration of Autologous Bone Marrow Stromal Cells in Chronic Paraplegia
Spinal Cord Injury
Primary: Safety-Number of Adverse Events — 69 Adverse events
Phase 2 N=159 A Study of A-101 Topical Solution Administered Twice a Week in Subjects With Common Warts
Common Wart
Primary: Physician's Wart Assessment — 1.52; 2.23 score on a scale
N/A N=48 A Study to Investigate a Method to Measure Food Occlusion by Denture Adhesives in Denture Wearers
Denture Retention
Primary: Mass of Peanuts Under Combined Maxillary and Mandibular Dentures (Denture Adhesive Applied Per Conventional Pattern) — 0.01184; 0.00944; 0.07853 Grams
Phase 2 N=54 Pharmacodynamics, Safety, Tolerability, and Pharmacokinetics of Two Orally Inhaled Indacaterol Salts in Adult Subjects With Asthma.
Asthma
Primary: Trough FEV1 — 2.4173; 2.3774; 2.2191 Liters — p=<0.001
Phase 3 N=81 Evaluating the Effectiveness of Aripiprazole and D-Cycloserine to Treat Symptoms Associated With Autism
Autistic Disorder
Primary: Mean Post-baseline Aberrant Behavior Checklist Irritability Score, Parent Report, Double-blind Phase — 25.5; 18.6 units on a scale
Phase 1 N=36 A Study to Evaluate the Effect of Itraconazole and Rifampin on the Pharmacokinetics of Talazoparib in Patients With Advanced Solid Tumors
Advanced Solid Tumors
Primary: Maximum Observed Plasma Concentration (Cmax) of Talazoparib: Alone and in Combination With Itraconazole — 2092.00; 2936.82 Picogram per milliliter (pg/mL)
Phase 2 N=212 Study To Evaluate Safety And Efficacy Of PF-06700841 In Subjects With Moderate To Severe Plaque Psoriasis
Chronic Plaque Psoriasis
Primary: Change From Baseline in Psoriasis Area and Severity Index (PASI) Score at Week 12 — -15.85; -10.56; -14.28; -10.14 units on a scale — p=0.0005
N/A N=14 Acupuncture on Cardiac and Autonomic Function in Human Heart Failure
Chronic Heart Failure
Primary: Change in Cardiac Function: LVEF — 36.14; 36.11; 40.59 LVEF Percentage — p=0.063
N/A N=216 The Effectiveness of Dual Therapy (Lopinavir/Ritonavir + LamivudinE) in Treatment-Experienced HIV Infected Patients in the Russian Federation
HIV-1 Infection
Primary: Percentage of Participants on Dual Therapy (LPV/r + 3TC) With Undetectable HIV-1 RNA Level at Week 48 — 100 percentage of participants
Phase 3 N=196 MEDITOXIN® Versus BOTOX® in the Treatment of Post-stroke Spasticity of the Upper Limb Spasticity
Spasticity
Primary: MAS(Modified Ashworth Scale) of Wrist Flexor — 2.41; 2.52; 1.02; 0.96 Scores on a MAS Scale — p=0.1347