Phase 4 N=20 Effect of Weight and/or Obesity on Anidulafungin Drug Concentrations
Obesity · Mycoses
Primary: Serum Clearance of Anidulafungin — 0.94 L/hr
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=50 The Immunological Basis for Treatment Resistance to Anti-TNF Treatments
Psoriasis
Primary: Change in Psoriasis Area and Severity Index (PASI) Score — 13.92; 4.43 units on a scale — p=0.38
Phase 1 N=160 Bioequivalence of Tablet Formulation of Dabigatran Etexilate Compared to Commercial Capsule Formulation Following Oral Administration in Healthy Male Subjects
Healthy
Primary: AUC0-tz of Free Dabigatran — 725.03686; 668.42714 Nanogram*hour/milliliter (ng･h/mL)
Phase 3 N=378 Naltrexone for Use in Conjunction With Buprenorphine in Adults With Opioid Use Disorder Prior to First Dose of VIVITROL® (Naltrexone for Extended-Release Injectable Suspension)
Opioid Use Disorder
Primary: Proportion of Subjects Who Receive and Tolerate a VIVITROL Injection — 57; 51; 57 Participants — p=0.940
Phase 2 N=632 A Phase II Study on Immunogenicity and Safety of MVA-BN® (IMVAMUNE™) Smallpox Vaccine in Subjects With Atopic Dermatitis
Atopic Dermatitis
Primary: Percentage of Participants With Seroconversion by ELISA — 98.5; 97.3 percentage of subjects
N/A N=7,443 OTIVACTO Regional Center Vienna (RCV) Non-Interventional Study (NIS)
Pulmonary Disease, Chronic Obstructive
Primary: Percentage of Patients With Therapeutic Success After Approximately 6 Weeks. — 67.76 Percentage of participants (%)
Phase 4 N=43 Treatment of Alcohol Dependence and Comorbid Bipolar Disorder
Alcohol Dependence · Bipolar Disorder · Depression
Primary: Percent Days Abstinent From Alcohol — 78.7; 80.1 Percentage of days abstinent
Phase 3 N=637 Co-crystal E-58425 vs Tramadol and Celecoxib for Moderate to Severe Acute Pain After Bunionectomy. Phase III Clinical Trial.
Acute Post-surgical Pain
Primary: Sum of Pain Intensity Differences (SPID) — -139.12; -109.08; -103.69; -74.55 units on a scale
N/A N=183 Study in Ankylosing Spondylitis (AS) and Psoriatic Arthritis (PsA) Patients to Evaluate Work Productivity Before and After the Start of Adalimumab Therapy in Daily Practice in Belgium
Ankylosing Spondylitis · Psoriatic Arthritis
Primary: Change From Baseline at Month 18 in TWPI Due to Disease (Ankylosing Spondylitis and Psoriatic Arthritis Combined) — -29.15 percentage of TWPI
N/A N=90 The Effect of Review of a Decision Aid Prior to the Appointment on Decisional Conflict Compared to Usual Care in the Treatment of Trapeziometacarpal (TMC) Arthritis
Trapeziometacarpal Arthritis
Primary: Decision Conflict Scale (DCS) — 9.3; 17 units on a scale
N/A N=257 Down Syndrome Metabolic Health Study
Down Syndrome · Trisomy 21
Primary: Non-HDL Cholesterol — 128; 107 mg/dl
N/A N=7 Safety of Post-transplant Alpha-beta Depleted T-cell Infusion Following Haploidentical Stem Cell Transplant (Haplo SCT)
Hematologic Neoplasms · Graft-Versus-Host Disease
Primary: Number of Participants That Experience Acute Haploidentical Alpha Beta Depleted Transplant (aGVHD) — 0 Participants
Phase 2 N=89 Fast-Fail Trials in Mood and Anxiety Spectrum Disorders; Kappa Opioid Receptor Phase 2a
ANXIETY DISORDERS (or Anxiety and Phobic Neuroses)
Primary: Change in Ventral Striatal Activation Occurring in Anticipation of Reward During the Monetary Incentive Delay Task Measured by fMRI — 0.718; 0.331 Z score — p=0.0095
Phase 3 N=106 A Safety and Efficacy Study of Multiple Administration Regimens for Nivolumab Plus Ipilimumab in Subjects With Melanoma
Melanoma
Primary: Percentage of Participants Affected by Adverse Events (AEs) in the Broad Scope MedDRA Anaphylactic Reaction Standardized MedDRA Queries (SMQ) — 15.1; 17.0 Percent of…
Phase 2 N=15 Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC Transplant
Acute Myeloid Leukemia · Acute Lymphoid Leukemia · Hematopoetic Myelodysplasia
Primary: The Percent of Subjects Engrafting by Day +30 After Transplantation — 100 percentage of participants