65,437 trials
Posttraumatic Stress Disorder · Major Depressive Disorder · Transcranial Magnetic Stimulation, Repetitive
Primary: Total Score on PTSD Checklist for DSM-5 (PCL-5) — 52.2; 34.0 units on a scale
Periodontal Disease · Type 2 Diabetes Mellitus
Primary: Glycated Hemoglobin A1c — 8; 8.2 percentage of Glycated Hemoglobin A1c
Healthy Volunteers
Primary: Number of Participants With One or More Serious Adverse Event(s) (SAEs) Considered by the Investigator to be Related to Study Drug Administration — 0; 0; 0; 0 participants
Arthritis, Rheumatoid
Primary: Satisfactory Vaccination Responses Against 3 Antigens — 31.5; 22.7; 51; 46.2 percentage of responders
Idiopathic Small Fiber Neuropathy
Primary: Visual Analogue Score for Pain Intensity. — 7.1; 6.9; 7.3; 5.4 score on visual analogue score
Yaws
Primary: Number of Participants With Clinical and Serological Cure — 68; 61 Participants
Onychophagia
Primary: Number of Participants Enrolled Within One Year — 12; 11 Participants
Healthy
Primary: Pharmacokinetics (PK): Maximum Observed Concentration (Cmax) of Evacetrapib — 748; 959 nanograms per milliliter (ng/mL)
Focus of Study · Coagulation Status of Cardiac Surgery Patient · Reducing Excess Blood Transfusion
Primary: Change in Thromboelastography-derived Functional Fibrinogen Level (FLEV) — -1.1 mg/dL
Anemia
Primary: Number of Participants With Clinically Significant Events — 4; 3; 6; 5 participants
Contraception · Unintended Pregnancy
Primary: Unintended Pregnancy — 46; 25 Participants
Actinic Keratosis
Primary: Percentage of Participants With Complete Resolution of Actinic Keratosis (AK) — 21.4; 3.4 percentage of participants — p=<0.001
Foot Dermatoses
Primary: Percent of "in Label" Adherent Subjects — 85; 60 percentage of participants
Dyslipidemia
Primary: Pharmacokinetics (PK) Parameters of Evacetrapib: Area Under the Concentration Versus Time Curve From Time Zero to the Last Time Point With a Measurable Concentration…
Lower Back Pain
Primary: Change in Pain Intensity Rating (Visit 6-Baseline) — 4.11; 4.67 units on a scale — p=0.02