65,437 trials
Metastatic Castration-resistant Prostate Cancer
Primary: Part A: Percentage of Patients Experiencing Adverse Events (AEs) — 66.7; 46.2; 33.3; 7.7 Percentage of patients
Schizophrenia
Primary: Change in Positive and Negative Syndrome Scale (PANSS) - Total Score - Study Phases 1 and 2 — 83.6; 79.8; 77.6; 76.7 units on a scale — p=0.57
Obstetric Labor, Premature
Primary: Number of Participants With Prevention of Preterm Delivery for 48 Hours With Attainment of Uterine Quiescence — 80; 72 Participants — p=0.01
Pneumococcal Infection
Primary: Number of Participants With Innate Immunity Signatures That Correlate With the Quality of Antibodies After PNEUMOVAX and PREVNAR - Monocyte Module M4.15 — 1; 2; 0; 2…
Nicotine Dependence · Nicotine Use Disorder
Primary: Biologically-verified 7-day Point Prevalence Smoking Abstinence — 10; 3; 3; 3 participants — p=0.07
Nodular Basal Cell Carcinoma · Superficial Basal Cell Carcinoma
Primary: Percentage of Lesions Cleared Histologically — 3; 5 Lesion
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) · Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Primary: Number of Adverse Events (AEs) Per Infusion — 0.032 Adverse events per infusion
Lumbar Degenerative Disc Disease
Primary: Number of Participants With a Change of at Least 15 Points in Pain/Disability Using the Oswestry Disability Index (ODI) Score at 24 Months Compared With the Score at…
Leukemia, Myeloid, Acute · Myelodysplastic Syndromes
Primary: Correlation of Patient Specific Mutations With Overall Response Rate — 26; 3; 9; 2 Participants — p=0.035
Myasthenia Gravis
Primary: Steroid Sparing Effect — 15; 15 Participants — p=0.03
Primary Angle-Closure Glaucoma · Primary Angle Closure Without Glaucoma Damage
Primary: Change in Intraocular Pressure Between Baseline and 1 Year — 15; 14.7 mmHg
Relapsed or Refractory Chronic Lymphocytic Leukemia
Primary: Number of Participants With Treatment-emergent Adverse Events — 34; 34; 35; 33 Participants
Solid Malignancy · Solid Tumor
Primary: Response Rate (RR) — 1 Participants
Cystic Fibrosis
Primary: Absolute Change From Study Baseline in Percent Predicted Forced Expiratory Volume in 1 Second (ppFEV1) Through Week 8 — 2.6; 2.7 Percentage of predicted FEV1 — p=0.9277
Epistaxis · Blood Pressure
Primary: Change in Mean Arterial Blood Pressure — 5.1; 6.4; 4.6; 6.5 mmHg — p=0.42