Phase 2 N=227 Safety and Efficacy of RGH-188 (Cariprazine) in Bipolar Depression
Bipolar Depression
Primary: Change From Baseline in Montgomery-Asberg Depression Rating Scale (MADRS) — 29.9; 30.2; 30.9 Score on scale — p=0.7408
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=1,987 Intermittent Auscultation Using Handheld Doppler: a Randomized Controlled Trial Comparing Perinatal Outcomes in Uganda
Stillbirth · Neonatal Death
Primary: Stillbirth and Neonatal Death — 6; 11 Participants
N/A N=300 Electrophysiological Effects of Late PCI After MI
Cardiovascular Diseases · Heart Diseases · Myocardial Infarction
Primary: Short-termed Fractal Scaling Exponent (Alpha 1) — 0.01; -0.03 unit-less — p=0.34
N/A N=420 Causes of Rotavirus Vaccine Failure in Zambian Children
Diarrhoea
Primary: Proportion of Immunized Infants Exposed to High Breast Milk Anti-rotavirus Immunoglobulin-A Who Fail to Seroconvert — 0.602 Proportion of exposed infants
N/A N=120 The Penumbra Liberty Trial: Safety and Effectiveness in the Treatment of Wide-Neck Intracranial Aneurysms
Wide-neck, Saccular Intracranial Aneurysms
Primary: Number of Participants With Raymond Class I Complete Obliteration at 12 Months — 98 Participants
Phase 2 N=64 Pharmacokinetics, Relative Bioavailability and Safety of Xaracoll Implant
Hernioplasty
Primary: Cmax — 340.4; 524.8; 348.4 ng/mL
Phase 2 N=5 A Study of Vitamin C in the Treatment of Liver Cancer to Determine if it is Safe and Effective
Metastatic Hepatocellular Carcinoma · Advanced Liver Cancer
Primary: Number of Participants That Experience Serious Adverse Events.
Phase 2 N=30 Atomoxetine Treatment for Cognitive Impairment in Parkinson's Disease (ATM-Cog)
Parkinson's Disease · Cognitive Impairment
Primary: The Global Statistical Test Combined Information on Change From Baseline on a Battery of Standardized Executive Function Tests — 99.5; 117.5 summed-ranks — p=0.25
Phase 2 N=248 The Long-term Antibody Persistence of GSK Biologicals' Meningococcal Vaccine GSK134612 in Healthy Toddlers
Infections, Meningococcal
Primary: Number of Subjects With Serum Bactericidal Assay (Using Human Complement) (hSBA) Titers ≥ the Cut-off — 21; 28; 91; 103 Participants
N/A N=100 The Effect of the Hyperinsulinemic Normoglycemic Clamp on Myocardial Function and Utilization of Glucose
Hyperglycemia · Aortic Valve Replacement · Aortic Stenosis
Primary: Myocardial Function: Left Ventricular Global Longitudinal Strain (%) — -16.8; -15.9 percentage of myocardial shortening — p=0.11
N/A N=108 Transcranial Magnetic Stimulation Effects on Pain Perception
Gastric Bypass Surgery Pain Management
Primary: Patient Controlled Analgesia (PCA) Hydromorphone Usage — 11.77; 13.42; 12.66; 9.83 mg/ml
Phase 2 N=208 A Dose-ranging Study With Brivaracetam in Patients From 16 to 65 Years With Refractory Partial Onset Seizures.
Epilepsy
Primary: Partial Onset Seizure Frequency Per Week During the 7-week Treatment Period — 1.81; 1.61; 1.55; 0.92 Seizures per week — p==0.240
Phase 4 N=140 ADA Linagliptin in Long Term Care
Diabetes
Primary: Mean Fasting Blood Glucose Level — 136.4; 131.2 mg/dl
N/A N=49 Vestibular Rehabilitation and Dizziness
Dizziness
Primary: Visual Analog Scale - Head Movement — 1.56; 1.81 units on a scale — p=.356
Phase 4 N=93 Parasternal Nerve Block Using Bupivacaine for Postoperative Analgesia in Children Undergoing Cardiac Surgery
Pain
Primary: Total Fentanyl/Equivalent Day 0-1 — 23.6; 22.4 mcg/kg/day