65,437 trials
Severe · Symptomatic · Calcific Aortic Stenosis
Primary: Number of Participants With All-Cause Mortality and/or Major Stroke and/or Rehospitalization — 105; 102 participants
Symptomatic Severe Aortic Stenosis
Primary: Number of Participants With Composite of All-cause Death, All Stroke and Aortic Insufficiency (AI) ≥ Moderate — 125 Participants
Fibromyalgia
Primary: Change From Baseline to 13 Week Endpoint in Brief Pain Inventory (BPI) Modified Short Form-adolescent Version 24 Hour Average Pain Severity Item — -1.62; -0.97 units on…
Symptomatic Severe Aortic Stenosis
Primary: All-cause Death or Disabling Stroke to Two Years — 192; 202 Participants
Chronic GVHD
Primary: Proportion of Participants With Treatment Success — 33; 35; 33; 37 Participants — p=0.63
Rotator Cuff Tendinitis
Primary: Visual Analog Pain Scale 0= no Pain 10 = Maximum Pain — 7.3; 6.9; 6.9 units on a scale
Asthma
Primary: Maximum Observed Plasma Concentration (Cmax) of Mepolizumab — 11.57; 11.98; 12.07 micrograms per milliliter (µg/mL)
Exocrine Pancreatic Insufficiency · Cystic Fibrosis
Primary: Treatment Difference in Coefficient of Fat Absorption (CFA) Change From Baseline — -11.852 percent change from baseline
Pediatrics · Muscle Spasticity · Cerebral Palsy
Primary: Average Change From Baseline in Modified Ashworth Scale-Bohannon (MAS-B) Ankle Score With Knee Extended at Weeks 4 and 6 — -1.06; -1.01; -0.80 score on a scale — p=0.010
Refractive Errors · Myopia · Hypermetropia
Primary: Ex Vivo Total Cholesterol Uptake at Day 30 — 0.28; 0.28; 2.17; 4.18 μg — p=<0.0001
Symptomatic Severe Aortic Stenosis
Primary: The Composite Rate of All-cause Mortality, All Stroke, and AI ≥ Moderate — 6.7 percentage of patients
Abscess · Wound Infection · Surgical Site Infection
Primary: Percentage of Participants Who Were Clinical Responders 48-72 Hours After the Initiation of Study Drug — 81.4; 84.2 percentage of participants
Male Hypogonadism
Primary: Percentage of Treated Patients With Average Serum Testosterone (T) Concentrations (Cavg) Between 300 and 1000 ng/dL — 83.6; 79.2 percentage of partipants
Bipolar Disorder · Mania
Primary: Sedation Score — 0.5; 0.5; 0.6; 0.6 units on a scale
Low Birth Weight
Primary: Infant Weight — 6.92; 7.32 kg