65,437 trials
Asthma, Aspirin-Induced · Aspirin Exacerbated Asthma
Primary: Difference in PD2 (Provocative Dose of Aspirin That Elicits an Increase in Nasal Symptom Score of 2 During an Aspirin Challenge) on Prasugrel Versus Placebo — 79; 139 mg
Diabetes · Diabetes Mellitus, Type 1
Primary: Change in Glycosylated Haemoglobin (HbA1c) — 7.49; 7.49; -0.06; -0.14 Percentage (%) of HbA1c
Cystic Fibrosis
Primary: Kinetic Influx Constant (Ki) — 0.009; 0.013 mL/min/mL
Ulcerative Colitis
Primary: Percentage of Participants Within Each of Nine Pre-specified Adverse Event (AE) Categories — 9.1; 3.4; 10.5; 13.0 Percentage of participants
Pre-diabetes · Overweight · Obese
Primary: Count of Participants Who Completed the Study — 28; 33 Participants
Endometrial Cancer · Cervical Cancer
Primary: Estimate the Sensitivity of the Sentinel Lymph Node — 418 Participants
Adenocarcinoma of the Gastroesophageal Junction · Esophageal Cancer
Primary: Comparison of Progression-free Survival — 6.1; 2.4 Months — p=0.43
Rapidly Escalating Migraine
Primary: The Percentage of Subjects Reporting Pain Freedom at 60 Minutes Post-treatment — 50; 52.63 Percentage of responders
Venous Thromboembolism · Pulmonary Embolism
Primary: Number of Participants With Treatment-related Bleeding Events as Assessed by the Need for Blood Transfusions and Procedures for Bleeding Complications After Initiation…
Type II Diabetes Mellitus
Primary: Change From Baseline in Glycosylated Hemoglobin (HbA1c) at Week 24 — -0.0003; -0.0030; -0.0275 percentage of glycosylated hemoglobin
Coronary Artery Disease · Coronary Artery Stenosis · Coronary Disease
Primary: Number of Participants With Target Lesion Failure (TLF) — 64; 48 Participants — p=0.0244
Adult Acute Megakaryoblastic Leukemia (M7) · Adult Acute Minimally Differentiated Myeloid Leukemia (M0) · Adult Acute Monoblastic Leukemia (M5a)
Primary: Inhibition of NF-kB Target Transcripts and/or Inhibition of Drug Efflux in at Least 50% of Patients — 13; 14 Participants — p=<.05
Intraocular Pressure
Primary: Change in Mean Diurnal IOP at Visit 6 (Day 28) — -7.829; -8.295; -8.952; -8.894 mm Hg
Alcohol Dependence
Primary: Heavy Drinking Days Per Week — 0.23; 0.33 days/week
Pain
Primary: Total Opioid Intake in Morphine Milligram Equivalents in the First 48 Hours After Cesarean Delivery (CD) — 42; 49.5 morphine milligram equivalents