Early Phase 1 N=41 Study of Biotene OralBalance Gel for Oral Care in Critically-Ill Mechanically Ventilated Neonates
Ventilator-associated Pneumonia
Primary: Feasibility — 100; 100 percentage of participants retained
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Early Phase 1 N=30 Light for Renal Transplant Recipients Having a Sleep-Wake Dysregulation
Renal Disease · Sleep Disorders
Primary: Bedtime — 7.44; 7.24; 22.98; 22.48 Hours
Early Phase 1 N=13 Breast Cancer, Aromatase Inhibitor Therapy, and Sexual Functioning: The Effects of Vaginal Testosterone Therapy
Breast Cancer · Vaginal Dryness · Dyspareunia
Primary: Total Female Sexual Function Index (FSFI) Score — 8.691; 18.783 units on a scale — p=<0.0005
Early Phase 1 N=10 A Pilot Clinical Trial for Poorly Differentiated Thyroid Cancer - Correlation to Retinoid and Peroxisome-proliferator-activated Receptor (PPARy) Expression
Thyroid Cancer
Primary: Change in Tumor Size — 4.7 cm
Early Phase 1 N=7 A Pilot Study to Determine the Safety and Tolerability of Sirolimus Given With Hyper-CVAD Chemotherapy
Lymphoid Malignancies (New or Relapsed) · Acute Lymphoblastic Leukemia · Burkitt Lymphoma
Primary: Number of Participants With Count Recovery That Allows for Starting a Phase II Study to Evaluate Response Rates and Survival — 7 participants
Early Phase 1 N=28 Pentoxifylline Treatment of Acute Pancreatitis
Acute Pancreatitis
Primary: Change in C-Reactive Protein (CRP) — 48.4; 60.6; 62; 154 mg/L — p=0.62
Early Phase 1 N=14 Renal Salt Handling in Postural Tachycardia Syndrome Following Dietary Dopa Administration
Healthy Participants
Primary: Plasma Dopa 1 hr After Breakfast — 11670; 1705 pg/mL
Early Phase 1 N=13 Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain
Brain and Central Nervous System Tumors · Cognitive/Functional Effects · Long-term Effects Secondary to Cancer Therapy in Children
Primary: Neurocognitive Function as Measured by the Neurocognitive Battery at 24 Weeks — 10 units on a scale
Early Phase 1 N=53 Dronabinol Interactions With Cognitive Enhancing Drug in Humans
Cannabis · Marijuana Abuse
Primary: CANTAB:CAmbridge Neuropsychological Test Automated Battery RVIP: Rapid Visual Information Processing — 0.91; 0.9; 0.92; 0.9 units on a scale
Early Phase 1 N=70 Evaluation of Adherence to Topical Agents: Applying Communication Technology to Improve Sunscreen Use
Skin Cancer
Primary: Number of Days the Subjects Are Adherent to Using Sunscreen — 12.6; 23.6 days
Early Phase 1 N=32 A Preliminary Study of 18F-AV-45 in Alzheimer's Disease and Healthy Elderly Volunteers
Alzheimer Disease
Primary: Mean Cortical to Cerebellum SUVR — 1.665; 1.246 SUVR
Early Phase 1 N=28 Angiogenic and EGFR Blockade With Curative Chemoradiation for Advanced Head and Neck Cancer
Head and Neck Cancer · Pharynx Cancer
Primary: Tumor Resolution — 25 Participants
Early Phase 1 N=15 Mitomycin C With Hyperthermia and Intravesical Mitomycin C to Treat Recurrent Bladder Cancer
Transitional Cell Carcinoma of Bladder · Superficial Bladder Cancer
Primary: Safety and Tolerability — 5; 2; 1; 1 Grade 1/2 event count (no grade 3+)
Early Phase 1 N=12 Vitamin D Repletion in Chronic Kidney Disease
Chronic Kidney Disease
Primary: Change in Endotoxin Activity — -.057 EA units
Early Phase 1 N=66 Effects of Rocking on Postoperative Ileus Duration Study
Abdominal Cancer
Primary: Time to First Postoperative Flatus in Days Was the End of Postoperative Ileus (POI) Indicator. — 3.16; 3.88 Days — p=<0.05