65,437 trials
Hepatitis C Virus Infection
Primary: Percentage of Participants With Sustained Virologic Response (SVR) 12 Weeks After Discontinuation of Therapy (SVR12) — 96.4; 96.3 percentage of participants — p=<0.001
Depressive Disorder, Major
Primary: Change From Randomization (Week 0) Associated With GW856553 Versus Placebo at Week 6 in the Bech (6-item HAMD-17 [Hamilton Depression Rating Scale]) Score. — -6.5; -5.6…
Exudative Age-Related Macular Degeneration
Primary: Number of Subjects With Positive LUCENTIS® Retreatment Status at Day 84 — 25; 25 Participants
Actively Extending Plaque Psoriasis · Moderate to Severe Plaque Psoriasis
Primary: Mean Epidermal Thickness at End-of-Treatment (EOT) Compared to Pre-treatment — -8.8; -48.5; 17.3 Millimeters
Sepsis · Severe Sepsis
Primary: 100% f T>MIC: Free Piperacillin Concentration Maintained Above the MIC Throughout the Dosing Interval. — 4 participants
Obesity
Primary: Change in Body Weight — -0.99; -2.6; -1.7 kg
Bipolar Depression
Primary: Montgomery-Asberg Rating Scale for Depression (MADRS) — 24.3 units on a scale
Seborrheic Keratosis
Primary: Proportion of Subjects With Target Lesion Clearance as Assessed by the Physician Lesion Assessment — 9; 0 Participants
Recurrent B-Cell Non-Hodgkin Lymphoma · Recurrent Chronic Lymphocytic Leukemia · Recurrent Indolent Adult Non-Hodgkin Lymphoma
Primary: Objective Response Rate — 97; 39 percentage of participants
Acute Coronary Syndrome
Primary: Number of Participants With Non Coronary Artery Bypass Graft-Related (Non CABG-related) Thrombolysis in Myocardial Infarction (TIMI) Clinically Significant Bleeding…
HIV Infection
Primary: Number of Participants With Serum Creatinine Event of Grade 1 or Higher Over the Course of the Study — 0 Participants
Brain and Central Nervous System Tumors
Primary: (Phase III) Overall Survival (OS) — 3.9; 3.8 years — p=0.36
Psoriasis
Primary: Percentage of Participants Who Have a Physician Global Assessment (PGA) Score of 0 or 1 at Week 12 and a Minimum 2-grade Improvement in PGA Score From Baseline to Week…
Central Line-Associated Bloodstream Infection
Primary: Percentage of Therapeutic Failures (Early or Late Failure) in Children and Adolescents With CLABSI Receiving Standard Care Plus Ethanol Lock Therapy (ELT) vs. Standard…
Distal Radius Fractures
Primary: Average Difference Between Michigan Hand Outcomes Questionnaire Scores — 85.2; 91.8 units on a scale