N/A N=15 The Baltimore HEARS Pilot Study
Age-related Hearing Impairment 1 · Personal Communication
Primary: Change From Baseline in Hearing Handicap Inventory for the Elderly (HHIE)-S at 3 Months — -8.5; 0.3 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=700 Dose Ranging Study Evaluating the Efficacy and Safety of GSK2190915 Administered Once Daily
Asthma
Primary: Mean Change From Baseline to the End of the 8-Week Treatment Period in Trough Forced Expiratory Volume in One Second (FEV1) — 0.12; 0.18; 0.23; 0.19 Liters — p=0.326
Phase 2 N=6 Nalrexone Facilitated Discontinuation of Buprenorphine
Stable Opioid Dependence
Primary: Successful Discontinuation of Buprenorphine — 6 Participants
Phase 4 N=1,107 Rapid Empiric Treatment With Oseltamivir Study (RETOS)
Influenza · Pneumonia
Primary: Number of Participants With Clinical Failure (Failure to Reach Clinical Stability) — 6; 2 Participants — p=.460
Phase 2 N=15 Study of Quetiapine Treatment for Cannabis Dependence
Cannabis Dependence
Primary: Maximum Tolerated Dose of Quetiapine — 197 milligrams
Phase 2 N=228 A Study to Evaluate Aprepitant for the Prevention of Post-Operative Nausea and Vomiting in Children (MK-0869-219)
Post-operative Nausea · Post-operative Vomiting
Primary: Area Under the Concentration-time Curve of Aprepitant From Time 0 to the Last Measurable Concentration (AUC0-last) Following Administration of 125 mg Dose Equivalent in…
Phase 2 N=76 Effect of Isotretinoin on Immune Activation Among HIV-1 Infected Subjects With Incomplete CD4+ T Cell Recovery
HIV-1 Infection
Primary: Change in CD8+ T-cell Activation From Baseline to Week 14/16 — 3.24; 0.52 percentage of cells — p=0.030
Phase 4 N=14 Varenicline Effects In Schizophrenic Smokers
Schizophrenia · Tobacco Use Disorder · Nicotine Dependance
Primary: Self Report of Smoking — 36.45; 17.25; 12.52 Cigarettes
N/A N=279 Pivotal Study of a Percutaneous Mitral Valve Repair System
Mitral Valve Insufficiency · Mitral Valve Regurgitation · Mitral Valve Incompetence
Primary: Number of Participants With Major Adverse Events (MAE) — 13; 45 Participants
N/A N=55 Investigation of Two New 1-piece Ostomy Products in People With an Ileostomy or Colostomy
Ileostomy · Colostomy
Primary: Fit to Body — 93; 88; 57 percentage of good or very good
Phase 3 N=125 A Study Using Botulinum Toxin Type A as Headache Prophylaxis in Adolescents With Chronic Migraine
Migraine Disorders
Primary: Change From Baseline in the Frequency of Headache Days — 23.2; 23.4; 25.3; -6.3 Headache days
Phase 3 N=508 Open-label Study of the Safety and Efficacy of Adalimumab in the Treatment of Hidradenitis Suppurativa
Hidradenitis Suppurativa
Primary: Percentage of Participants in the EW/EW/EW, EW/EOW/EW, and EW/PBO/EW Analysis Populations Achieving Clinical Response Per Hidradenitis Suppurativa Clinical Response…
Phase 2 N=19 Effect of Zonisamide on Cocaine Reinforcement, Craving, and Relapse
Cocaine Dependence
Primary: Change in Visual Analog Questionnaire (VAQ) Score — 0.38; 3.75; 0.38; 40.63 units on a scale — p=<0.01
N/A N=49 Patient-operated Valved Catheter Versus Indwelling Transurethral Catheter
Bladder Dysfunction · Urinary Retention
Primary: Total Catheter Related Pain — 1.25; 2.3 units on a scale
N/A N=15 L-arginine in Treatment as Usual in Schizophrenia
Schizophrenia
Primary: Change From Baseline in Mean Positive and Negative Syndrome Scale (PANSS) Total and Positive, Negative and General Psychopathology Subscale Scores at 3 Weeks — 71.6…