N/A N=21 Non-invasive Quantification of Liver Iron With MRI
Iron Overload
Primary: Per Subject Evaluable DICOM Data Sets From Liver MRI — 21 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=150 Palliative Care in Heart Failure
Heart Failure · Heart Diseases · Cardiovascular Diseases
Primary: Change in Kansas City Cardiomyopathy Questionnaire (KCCQ) — 36.1; 31.4; 63.1; 52.1 units on a scale — p=0.1641
Phase 4 N=113 Posaconazole Versus Micafungin for Prophylaxis Against Invasive Fungal Infections During Neutropenia in Patients Undergoing Chemotherapy for Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia or Myelodysplastic Syndrome
Acute Myelogenous Leukemia · Myelodysplastic Syndrome
Primary: Time to Failure — 16; 13 Days
Phase 3 N=142 Self-Administered Lidocaine Gel for Pain Management With First Trimester Surgical Abortion: A Randomized Controlled Trial
Pregnancy, Unwanted
Primary: Difference in Pain Level at Time of Cervical Dilation as Measured by a Visual Analog Scale — 68; 65 units on a scale
Phase 2 N=140 Comparison of Psychological and Pharmacological Treatments for Pain Due to Temporomandibular Joint Disorder (TMD)
Temporomandibular Joint Disorders
Primary: Average Pain — 4.7; 4.4; 4.5; 5.0 units on a scale — p=<.05
Phase 2 N=38 Erlotinib Hydrochloride and Bevacizumab in Treating Patients With Stage IV Breast Cancer
Recurrent Breast Carcinoma · Stage IV Breast Cancer
Primary: Level of EGFR Expression — 24; 8; 4; 0 participants
Phase 2 N=134 Fruit and Vegetable Extracts in Treating Patients With Stage I-IV, Stage IVA/IVB Head and Neck Cancer
Head and Neck Cancer
Primary: Expression of p27 Cell Cycle Regulatory Protein at Baseline and Week 12 — 18.6; 15.1; 17.0; 14.5 percentage of cells
N/A N=281 Continuous Positive Airway Pressure to Improve Milder Obstructive Sleep Apnea
Lung Diseases · Sleep Apnea Syndromes · Hypertension
Primary: Change in the Score of the Functional Outcomes of Sleep Questionnaire at Baseline and Week 8 Treatment — 0.98; -0.14 scores on a scale
N/A N=210 Physical Health in Midlife: Influences of Adversity and Relationships Over Time
Cardiovascular Disease · Type 2 Diabetes
Primary: Hormonal Levels — 910000; 5.8; 22.8; 171.8 ng/ml
N/A N=74 Problem Adaptation Therapy (PATH) vs. Supportive Therapy in Treating Depressed, Cognitively Impaired Older Adults
Depression
Primary: Montgomery Asberg Depression Scale (MADRS) — 10.46; 15.53 Units on MADRS scale — p=0.005
Phase 3 N=577 A Study Comparing Dulaglutide With Insulin Glargine on Glycemic Control in Participants With Type 2 Diabetes (T2D) and Moderate or Severe Chronic Kidney Disease (CKD)
Type 2 Diabetes · Chronic Kidney Disease
Primary: Change From Baseline in Hemoglobin A1c (HbA1c) — -1.13; -1.12; -1.19 percentage of HbA1c — p=<0.001
Phase 2 N=7 BRAF Inhibitor, LGX818, Utilizing a Pulsatile Schedule in Patients With Stage IV or Unresectable Stage III Melanoma Characterized by a BRAFV600 Mutation
Melanoma
Primary: Number of Participants With Response According to RECIST v1.1 Criteria — 2; 2; 2; 1 Participants
N/A N=34 Exercise-induced Hypoalgesia After Comparative Forms of Exercise
Pain
Primary: Change in Pain Intensity Ratings (0-100 Pain Scale) — 33.5; 46.2; 40.2 scores on a scale
Phase 3 N=2,139 Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Hyperlipidemia or Mixed Dyslipidemia at Risk of Cardiovascular Events
Hyperlipidemia
Primary: Percent Change From Baseline in Fasting Low Density Lipoprotein Cholesterol (LDL-C) at Week 12 — 1.0; -54.9 percent change — p=<0.001
N/A N=62 Diagnostic Use of Lung Ultrasound for Suspected Pneumonia in Nepal
Pneumonia
Primary: Diagnosis of Pneumonia — 40; 32; 4; 12 Participants