Phase 4 N=27 Dose Response Effects of Quillivant XR in Children With ADHD and Autism: A Pilot Study
ADHD · Autism
Primary: ADHD Rating Scale - IV — 17.89; 16.78; 16.67; 14.33 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=30 Busulfan and Etoposide Followed by Peripheral Blood Stem Cell Transplant and Low-Dose Aldesleukin in Treating Patients With Acute Myeloid Leukemia
Adult Acute Myeloid Leukemia in Remission · Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities · Adult Acute Myeloid Leukemia With Del(5q)
Primary: Overall Survival of Patients on Busulfan and Etoposide Followed by Stem Cell Rescue and Aldesleukin — 14 Participants
Phase 2 N=87 Comparison of PET Amyloid Imaging in Japanese and Western Subjects
Mild Cognitive Impairment · Alzheimer's Disease · Healthy
Primary: Blinded Visual Assessment of Positron Emission Tomography (PET) Imaging and Clinical Diagnosis by Non-Japanese Readers — 23; 0; 2; 25 Participants
N/A N=40 Influence of Timing on Motor Learning
Cerebrovascular Accident
Primary: Motor and Strength Outcome Measure Using Box and Block Test — 2.3; 4.3 blocks
Phase 2 N=54 fMRI Study Examining Effects of D-cycloserine in Specific Phobia
Phobias
Primary: fMRI Brain Activations During Symptom Provocation — .200; .157; -.013; .036 percent signal change
Phase 3 N=187 Extension Study of Eculizumab in Patients With Transfusion Dependent Paroxysmal Nocturnal Hemoglobinuria (PNH)
Paroxysmal Hemoglobinuria, Nocturnal
Primary: Incidence of Treatment-emergent Adverse Events — 182 Participants
Phase 3 N=294 Progesterone vs Placebo Therapy for Women With Epilepsy
Epilepsy
Primary: Percent of Women Who Show a Greater Than 50% Decline in Average Daily Seizure Frequency — 22.8; 20.0; 20.2; 19.2 percentage of participants
N/A N=240 Quantitative Study of New Limbal Ring Prototypes
Cosmetic Effect
Primary: Number of Subject in Agreement (Bigger Eyes) — 187; 213; 206; 209 Participants
N/A N=32 Neurobiological Bases of Paternal Nurturance
Healthy
Primary: Mean Percent Signal Change in Ventral Tegmental Area (VTA) — 0.54; 0.27 Percent signal change
Phase 2 N=13 Clomiphene Citrate for the Treatment of Low Testosterone Associated With Chronic Opioid Pain Medication Administration
Hypogonadism · Opioid-Related Disorders · Male Infertility
Primary: Serum Total Testosterone (Change From Baseline) — 322.5; 179.8 ng/mL
Phase 2 N=40 Sirolimus Versus Anti-Vascular Endothelial Growth Factor (antiVEGF) for Wet AMD
Age-Related Macular Degeneration
Primary: Change in Edema From Baseline to Month 6 Central Subfield Thickness ) on Heidelberg Optical Coherence Topography — -30.0; 7.5 microns
N/A N=168 Trans-obturator Mid-urethral Sling and the Single-incision Sling in Women With Stress Urinary Incontinence
Urinary Incontinence, Stress
Primary: Percentage of Participants With Negative Cough Stress Test (CST) — 86.4; 83.1 percentage of participants
Phase 2 N=730 Trizivir Vs. Kaletra and Combivir for the Prevention of Mother-to-Child Transmission of HIV
HIV Infections
Primary: Number of Participants With Virologic Suppression — 274; 256; 160 Participants
Phase 2 N=71 Vaccination Response in Tecfidera-Treated Versus Interferon-Treated Participants With Relapsing Forms of Multiple Sclerosis.
Relapsing Forms of Multiple Sclerosis
Primary: Percentage of Tetanus Responders (≥ 2-Fold Rise) at Day 28 Compared to Prevaccination Level — 73; 68 percentage of participants — p=0.692
N/A N=232 An RCT on Preventing Pressure Ulcers With Wheelchair Seat Cushions
Pressure Ulcer
Primary: Sitting-induced Pressure Ulcers — 8; 1 participants — p=0.04