Phase 4 N=60 A Study of Brentuximab Vedotin in Participants With Relapsed or Refractory Hodgkin Lymphoma
Hodgkin Lymphoma
Primary: Objective Response Rate (ORR) — 50 percentage of participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=102 A Double Blind Study Comparing Hyaluronic Acid, Corticosteroid and Placebo During Arthrocentesis for Temporomandibular Joint (TMJ) Dysfunction
Temporomandibular Joint Dysfunction · Pain · Arthrocentesis
Primary: Change in Pain Between Baseline and Month 1 Scores — -1.1; -1.7; -2.6; -2.0 units on a scale
Phase 2 N=135 A Clinical Trial To Evaluate PF-05089771 On Its Own And As An Add-On Therapy To Pregabalin (Lyrica) For The Treatment Of Pain Due To Diabetic Peripheral Neuropathy (DPN)
Diabetic Neuropathy, Painful
Primary: Daily Pain Numeric Rating Scale (NRS) — 6.17; 6.62; 6.35; 5.45 Unit on a scale
Phase 2 N=16 Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed Dose Combination Administered in Patients Infected With Chronic Genotype 1 or 4 HCV for Use in the Peri-Operative Liver Transplantation Setting
Hepatitis C Virus Infection
Primary: Percentage of Participants With Sustained Virologic Response (SVR) 12 Weeks After Discontinuation of Therapy (SVR12) — 87.5 percentage of participants
Phase 4 N=72 Memantine and Cognitive Dysfunction in Bipolar Disorder
Bipolar Disorder
Primary: California Verbal Learning Test (CVLT) at Week 12 — 11.88; 11.55; 11.63; 11.73 correct items
Phase 2 N=41 S1014 Abiraterone Acetate in Treating Patients With Prostate Cancer Who Have Undergone Initial Hormone Therapy
Prostate Cancer
Primary: Number of Patients With Undetectable PSA — 5 Participants
Phase 3 N=515 Meta-Iodobenzylguanidine (123I-mIBG) Scintigraphy Imaging in Patients With Heart Failure and Control Subjects Without Cardiovascular Disease
Heart Failure, Congestive
Primary: Relationship Between the Occurrence of Adverse Cardiac Event and 123I-mIBG Uptake on Planar Scintigraphy Categorized as High or Low Heart to Mediastinum (H/M) Ratio…
Phase 2 N=16 Double-blind Pilot Trial of Mirtazapine for the Treatment of Co-occurring AD/MDD.
Major Depressive Disorder · Alcohol Use Disorder
Primary: Drinks Per Drinking Day — 3.5; 4.4 Drinks per drinking day
Phase 3 N=112 Long Term Safety And Effectiveness Of Dysport® In Adults With Cervical Dystonia
Cervical Dystonia
Primary: TWSTRS Total Score at Week 4 and Week 12 for Treatment Cycles 1, 2 and 3. — 37.7; 30.1; 32.6; 27.0 units on a scale
Phase 2 N=18 Cell Therapy for Craniofacial Bone Defects
Cleft Palate · Trauma
Primary: Bone Regeneration — 1.5; 3.3 implant sites
N/A N=30 The Effect of Osteopathic Manual Therapy on Vascular Supply
Knee Osteoarthritis
Primary: Resistive Index (RI) — 1.30; 1.40; 1.30; 1.35 ratio — p=<0.05
Phase 1 N=30 A Study to Assess Bioavailability and Pharmacokinetics of CAT- 354
Asthma · Healthy
Primary: Absolute Bioavailability of CAT-354 After Subcutaneous Dose — 62.1; 60.1 percent bioavailability
Phase 3 N=30 Comparison of Aliskiren vs Negative Controls on Aortic Stiffness in Patients With MFS
Marfan Syndrome
Primary: Central Aortic Distensibility by MRI — 3.7; 4.7; 5.7; 5.1 (mmHg ^ -1) x 10 ^ -3
Phase 4 N=70 Safety and Efficacy of Benefix in Patients With Hemophilia B in Usual Care Settings in China
HEMOPHILIA B
Primary: Percentage of Participants Who Developed Factor IX Inhibitor — 3.3; 0.0; 0.0; 1.8 percentage of participants
N/A N=70 An Observational Study of Tarceva (Erlotinib) in Participants With Locally Advanced or Metastatic Adenocarcinoma Non-Small Cell Lung Cancer (ELEMENT)
Non-Squamous Non-Small Cell Lung Cancer
Primary: Progression-Free Survival (PFS) — 2.7 months