Phase 3 N=65 Lipoprotein-associated Phospholipase A2 (Lp-PLA2) Progenitor Cells and Coronary Atherosclerosis in Humans
Endothelial Dysfunction
Primary: Percentage Change in Coronary Artery Diameter — 3; 3 % change coronary artery diameter
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=35 Phase II Hedgehog Inhibitor for Myelodysplastic Syndrome (MDS)
Myelodysplastic Syndrome (MDS) · Chronic Myelomonocytic Leukemia (CMML)
Primary: Overall International Working Group (IWG) 2006 Response Rate — 0; 2; 19; 14 Participants
Phase 2 N=24 A Phase II Trial of Panobinostat and Lenalidomide in Patients With Relapsed or Refractory Hodgkin's Lymphoma
Adult Lymphocyte Depletion Hodgkin Lymphoma · Adult Lymphocyte Predominant Hodgkin Lymphoma · Adult Mixed Cellularity Hodgkin Lymphoma
Primary: Determine the Overall Response Rate (ORR), Including Complete Responses (CR) and Partial Responses (PR) — 16.7 percentage of patients
N/A N=362 Using Computers to Assist in Parental Smoking Cessation in a Pediatric Setting
Cigarette Smoking
Primary: Parental Smoking Quit Rate — 31; 20 Participants
Phase 2 N=10 68Ga-PSMA PET/CT or PET/MRI in Evaluating Patients With Recurrent Prostate Cancer
Recurrent Prostate Carcinoma
Primary: Average SUVmax of Ga68 PSMA Uptake Outside the Expected Normal Biodistribution — 12.4 SUVmax
N/A N=120 Endometrial Injury for Unexplained Infertility
Infertility
Primary: Measurement of Uterine Artery Pulsatility Index — 2.40; 2.35 index — p=<0.05
N/A N=262 Intervention to Improve Expression of End of Life Preferences for Homeless Persons
Healthy
Primary: Completion of Advance Directive — 15; 55 Participants — p=<0.05
Phase 2 N=30 A Phase 2 Intratumoral Injection PF-3512676 Plus Local Radiation in Low-Grade B-Cell Lymphomas
Lymphoma, Non-Hodgkin · Lymphoma · Lymphomas: Non-Hodgkin Follicular / Indolent B-Cell
Primary: Overall ObjectiveResponse (ORR) Rate — 0; 7; 19; 4 participants
N/A N=798 Communicating Risk Information for Obesity
Obesity
Primary: Intentions to Lose Weight - Effect of Study Arm on Outcomes — 3.06; 3.37; 3.26; 3.26 units on a scale — p=.0150
N/A N=8,790 Streptococcus Pneumonia: Effects of PCV13 on Pneumococcal Carriage
Nasopharyngeal Carriage of S. Pneumoniae
Primary: Nasopharngeal Colonization With PCV13 S. Pneumoniae — 20; 31; 166; 137 Participants — p=<0.05
Phase 2 N=62 A Study of Aflibercept in Combination With FOLFIRI in Patients With Second-Line Metastatic Colorectal Cancer in Japan
Colorectal Cancer Metastatic
Primary: Percentage of Participants With Overall Response — 8.3 percentage of participants
Phase 3 N=275 Efficacy and Safety of 20 mg Sumatriptan Powder Delivered Intranasally With the Bi-directional Device Compared With 100 mg Sumatriptan Tablets in Adults With Acute Migraine With or Without Aura
Migraine · Headaches
Primary: Mean Sum of Migraine Pain Intensity Differences (SPID)-30 — 10.80; 7.41 scores on a scale — p=<0.0001
Phase 4 N=249 Safety of Purified Meningococcal Vaccine With Serogroups ACWY, in 3,000 Filipino Subjects Aged > 2 Years
Infections, Meningococcal
Primary: Number of Subjects With Severe (Grade 3) Unsolicited Adverse Events — 0; 0; 0 Participants
N/A N=318 A Trial of Intravenous Fluids During Labor
Ketosis
Primary: C-Section — 23; 18 Participants — p=0.34
Phase 2 N=35 A Phase 2 Study of Amrubicin in Relapsed or Refractory Thymic Malignancies
Thymoma · Thymus Cancer · Thymic Carcinoma
Primary: Overall Response Rate (ORR) — 0; 6; 6 Participants