N/A N=22 Combination Therapy to Treat Sleep Apnea
Sleep Apnea, Obstructive
Primary: Model Prediction of Absence/Presence of OSA: Ventilation That Causes an Arousal From Sleep (Varousal) — 5.7; 5.2 L/min — p=0.05
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=32 Phase 2 Study of Glycomacropeptide Versus Amino Acid Diet for Management of Phenylketonuria
Phenylketonuria
Primary: Change in the Plasma Phenylalanine Concentration of PKU Subjects Fed the Glycomacropeptide Diet Compared With the Change When Fed the Amino Acid Diet — 62; -85 micro…
N/A N=16 Placebo Controlled Study of Atomoxetine in the Treatment of Mild to Moderate Cognitive Difficulties in Menopausal Women
Menopause · Cognitive Disturbances
Primary: Brown Attention Deficit Disorder Scale — 60.7; 55.6; 56.3; 58.8 T score
Phase 2 N=346 A Study Evaluating Efficacy of ABT-888 in Combination With Temozolomide in Metastatic Melanoma
Melanoma · Metastatic Melanoma · Skin Cancer
Primary: Progression-Free Survival (PFS): Time to Event — 54; 56; 53; 60 days — p==0.071
N/A N=38 Dose Dense Adjuvant CMF (Cyclophosphamide, Methotrexate, Fluorouracil) at 14 and 10-11 Day Intervals for Women With Early Stage Breast Cancer
Breast Cancer
Primary: The Number of Patients Who Completed 8 Cycles. — 29 participants
Phase 2 N=12 A Within Subject Comparison of Opioid Withdrawal in Opioid Dependent Individuals
Opioid Abuse · Opioid Dependence
Primary: Mean Peak Opioid Withdrawal Assessed by the Clinical Opiate Withdrawal Scale (COWS) — 12.6; 1.3 units on a scale
Phase 4 N=42 Dexamethasone and Pain Following Total Knee Arthroplasty
Acute Pain · Chronic Pain
Primary: Change in Visual Analogue Pain Score — 3.09; 4.80; 3.56; 5.5 units on a scale — p=0.052
N/A N=1,968 Special Investigation in Patients With Rheumatoid Arthritis (Working Productivity Activity Impairment)
Rheumatoid Arthritis
Primary: Change From Baseline in Work Productivity and Activity Impairment-Rheumatoid Arthritis (WPAI-RA) Questionnaire: Mean Percentage of Work Time Missed (Absenteeism) — 7.23…
N/A N=37 Endothelial Bleb Response With Toric Lenses
Ametropia
Primary: Endothelial Bleb Areas on Cornea: Session A- Open Eye — 0.1; 2.0; 0.2; 2.1 Percent Difference of Bleb Area
Phase 3 N=1,168 Cabazitaxel Versus Docetaxel Both With Prednisone in Patients With Metastatic Castration Resistant Prostate Cancer
Prostate Cancer
Primary: Overall Survival (OS) — 24.3; 24.5; 25.2 months — p=0.7574
Phase 4 N=54 T Cell Responses to Varicella Zoster Virus (VZV) Vaccine SLVP020
Herpes Zoster
Primary: Number of Participants Who Received Zostavax Immunization or Had Natural Exposure to VZV — 45; 9 Participants
Phase 2 N=8 Prospective Trial Comparing Response to Hyperbaric Oxygen Treatment in Patients With Interstitial Cystitis
Interstitial Cystitis
Primary: Global Response Assessment (GRA) — 0; 1; 1; 0 number of participants
Phase 2 N=12 Buprenorphine's Dose Response Curve
Opioid-related Disorders
Primary: Peak Change From Baseline in Drug Effect Assessed by Visual Analog Scale (VAS) — 17.75; 27.25; 29.63; 58.25 units on a scale
Phase 2 N=195 Treatment of Hypochondriasis With CBT and/or SSRI
Hypochondriasis
Primary: 25% Improvement on Both Whiteley Index and H-YBOCS-M — 21; 13; 20; 25 Participants
Early Phase 1 N=8 CCRC: A Project of the Treatment of HIV Enteropathy With ImmunoLin® Supplements
HIV
Primary: Number of Bowel Movements Per Day — 5.8; 2 bowel movements/day — p=0.008